Sjogren’s Syndrome News

January 4, 2021January 4, 2021

Health, Financial Impact of Acute Kidney Injury Similar With or Without Sjögren’s

In-hospital mortality, the length of a hospital stay, and hospitalization charges for people with acute kidney injury and Sjögren’s syndrome are no different from those without Sjögren’s, a large-scale database ... Read more

December 22, 2020January 11, 2021

Electrical Brain Stimulation Found to Safely Reduce Sjogren’s Fatigue

Sjogren's Syndrome News

A technique that delivers low electric currents to stimulate specific parts of the brain can safely reduce fatigue in people with primary Sjogren’s syndrome (pSS), a pilot study has found. ... Read more

December 21, 2020December 21, 2020

Higher Risk of Blood Clots With COVID-19 Infection Seen in Study

COVID-19 News, Sjogren's Syndrome News

People with Sjögren’s syndrome and other systemic autoimmune rheumatic diseases (SARDs) may be at a greater risk of severe complications from COVID-19 than people without these disorders, a study reports. ... Read more

December 14, 2020December 15, 2020

RSLV-132 Lowers Fatigue in Primary Sjögren’s Patients in Phase 2 Trial

Sjogren's Syndrome News

RSLV-132, an investigational treatment for autoimmune conditions, led to significant and clinically meaningful reductions in patient-reported fatigue in people with primary Sjögren’s syndrome, results from a Phase 2 clinical trial show. ... Read more

December 7, 2020December 8, 2020

Study Links Altered Gut Microbiome in Sjogren’s to Systemic Inflammation

Sjogren's Syndrome News

Primary Sjogren’s syndrome (pSS) patients have less diversity in their gut microbiome — with less abundant beneficial bacteria but more abundant opportunistic bacteria with pro-inflammatory activity — compared with healthy ... Read more

November 30, 2020November 30, 2020

Sjogren’s Foundation Welcomes Applications for 2021 Research Grants

Sjogren's Syndrome News

Applications for a next round of Sjögren’s Foundation research grants are being accepted from U.S. investigators working to better understand Sjögren’s syndrome, a chronic immune system disorder, and improve patients’ lives. ... Read more

November 26, 2020December 28, 2020

New $100M Program Aims to Improve Diversity in Clinical Trials

Sjogren's Syndrome News

A new $100-million program aims to improve the diversity of participants in U.S. clinical trials with the ultimate goal of achieving better health outcomes and parity in care for underserved patient ... Read more

November 23, 2020November 24, 2020

Sjogren’s Burden Determined by Organ Involvement, Fatigue, Pain, Study Suggests

Sjogren's Syndrome News

Primary Sjögren’s syndrome (pSS) syndrome can be classified based on the extent of organ involvement, fatigue, and pain, with symptoms varying substantially from patient to patient, a new study reports. ... Read more

November 16, 2020November 16, 2020

LO2A Drops Lessen Dry Eye Symptoms, Even Outperform Systane on Some Measures

Sjogren's Syndrome News

Wize Pharma‘s LO2A eye drops result in clinically meaningful improvements in dry eye signs and symptoms in people with Sjögren’s syndrome, topline results from an exploratory Phase 4 trial show. The ... Read more

November 9, 2020November 9, 2020

Hydroxychloroquine Lowers Cardiovascular Risk in Sjögren’s Patients, Study Suggests

Sjogren's Syndrome News

Long-term use of hydroxychloroquine significantly lowers the risk of coronary artery disease, the most common form of heart disease, in people with Sjögren’s syndrome, a data study in Taiwan suggested. Its ... Read more

November 2, 2020November 2, 2020

Study Links Immune Regulatory Molecule NEAT1 to Primary Sjogren’s

Sjogren's Syndrome News

An immune regulatory molecule known as NEAT1 is produced at greater levels in the immune T-cells of people with primary Sjogren’s syndrome, and these levels seem to correlate with disease ... Read more

October 26, 2020October 26, 2020

Seletalisib Shows Trend Toward Easing Primary Sjögren’s in Phase 2 Trial

Sjogren's Syndrome News

Using the PI3K-delta inhibitor seletalisib as an add-on to standard treatment showed a trend toward easing disease activity and dryness, and significantly lowered patient-reported fatigue in people with primary Sjögren’s ... Read more

October 19, 2020October 19, 2020

$3.7M NIH Grant Will Support Research to Pinpoint Genes Associated With Sjögren’s

Sjogren's Syndrome News

The National Institute of Arthritis and Musculoskeletal and Skin Diseases, a part of the National Institutes of Health, has awarded a $3.7 million grant to advance studies investigating which genes are ... Read more

October 12, 2020October 12, 2020

Endoscopic Irrigation Brings Long-term Oral Relief to Sjögren’s Patients in Trial

Sjogren's Syndrome News

The use of sialendoscopy, an endoscopic tool to examine and treat the salivary glands, can be used to irrigate the major salivary glands with saline to increase salivation and lessen oral ... Read more

September 30, 2020September 30, 2020

Signaling Molecule IL-38 Can Reduce Inflammation, May Be Therapy Target, Study Finds

Sjogren's Syndrome News

Interleukin-38, an immune signaling molecule known as IL-38, can reduce the inflammatory activity of a type of immune cells involved in primary Sjögren’s syndrome (pSS), and may be a therapeutic ... Read more