Sjogren’s Syndrome News

June 15, 2021June 15, 2021

Immune T-Cells May Be Useful Indicator of Disease Activity

Sjogren's Syndrome News

A subset of immune cells, called CD4+CD8+ T-cells, is increased in the blood of patients with Sjögren’s syndrome, and their levels seem to correlate with lower disease activity, according to ... Read more

June 8, 2021June 8, 2021

Altered Signaling in Immune Cells May Contribute to Sjögren’s

Sjogren's Syndrome News

Immune macrophages — immune cells that fight infection — can mount distinct responses to specific pathogens, based on how a single signaling molecule behaves over time in the presence of ... Read more

June 1, 2021June 1, 2021

Aggressive Treatment, Monitoring Key in Early-onset Sjögren’s, Study Suggests

Sjogren's Syndrome News

People with early-onset primary Sjögren’s syndrome may need more intensive glucocorticoid and immunosuppressant therapy, closer follow-up, and regular monitoring than is customary, due to greater immune system activation and a less ... Read more

May 25, 2021May 25, 2021

Potential Link Found Between Sjögren’s- and Age-associated Dry Mouth

Sjogren's Syndrome News

An accumulation of damaged, pro-inflammatory immune cells, called senescence-associated T-cells, in salivary glands likely underlies gland dysfunction and dry mouth symptoms commonly seen with aging and in Sjögren’s syndrome patients, ... Read more

May 18, 2021May 18, 2021

Epstein-Barr Virus Infection May Contribute to Sjögren’s, Study Finds

Sjogren's Syndrome News

Infections with the Epstein-Barr virus (EBV), the most common member of the herpes virus family, may contribute to the development of Sjögren’s syndrome by increasing the proportion of immune cells ... Read more

May 11, 2021May 11, 2021

Damaged Mitochondria May Drive Autoimmunity

Sjogren's Syndrome News

Abnormalities in how mitochondria are “recycled” by cells could contribute to autoimmune diseases like Sjögren’s syndrome, a new study indicates. The study, “IRGM1 links mitochondrial quality control to autoimmunity,” was published ... Read more

May 4, 2021May 5, 2021

Tooth Stem Cell Secretions May Help Treat Sjögren’s

Sjogren's Syndrome News

Signaling molecules secreted by stem cells in teeth have anti-inflammatory properties that could be useful for the treatment of Sjögren’s syndrome, recent research in mice shows. The findings were published ... Read more

April 27, 2021April 27, 2021

Stressful Life Events May Trigger Sjögren’s Onset in Women

Sjogren's Syndrome News

Women with primary Sjögren’s syndrome experience more negative stressful life events than healthy people in the year before symptom onset, and the number of these negative events is associated with more ... Read more

April 20, 2021April 20, 2021

Bacterial Molecule Can Slow Sjögren’s Progression, Preclinical Study Suggests

Sjogren's Syndrome News

Oral treatment with a molecule produced by bacteria, called colonization factor antigen I, can reduce or halt the progression of Sjögren’s syndrome, a mouse study suggests. Researchers believe these findings ... Read more

April 13, 2021April 13, 2021

Small Tear Glands Grown in Lab Could Aid in Studying Sjögren’s

Sjogren's Syndrome News

A newly established cellular model of the tear gland may be useful for studying Sjögren’s syndrome and other diseases in which the tear glands become damaged, according to researchers. The ... Read more

April 6, 2021April 6, 2021

COVID-19 Vaccine Response Can Be Affected by Certain Medications

COVID-19 News, Sjogren's Syndrome News

Most patients with Sjögren’s syndrome and other rheumatic diseases develop anti-viral antibodies after their first COVID-19 vaccine shot, but their treatment affects the chances of them developing antibodies, a recent ... Read more

March 30, 2021March 30, 2021

Guidelines Issued for Managing Lung Symptoms

Sjogren's Syndrome News

The Sjögren’s Foundation has developed clinical practice guidelines for healthcare providers to improve the diagnosis, evaluation, and care of Sjögren’s syndrome patients with lung manifestations. The guidelines, which include 52 ... Read more

March 23, 2021March 23, 2021

Gene Variant May Increase Lymphoma Susceptibility in Young-onset Sjögren’s

Sjogren's Syndrome News

A variant of the LILRA3 gene may be associated with greater lymphoma susceptibility in a group of Sjögren’s syndrome patients with disease onset prior to age 40, a study reports. ... Read more

March 16, 2021March 16, 2021

Patients’ Stories Sought for Sjögren’s Awareness Month

COVID-19 News, Sjogren's Syndrome News

In observance of Sjögren’s Awareness Month in April, the Sjögren’s Foundation is inviting individuals with to share their stories to help raise awareness about this complex condition. This year’s theme, “Coming ... Read more

March 9, 2021March 9, 2021

Vitamin B12 Deficiency Linked With Primary Sjögren’s Syndrome in Study

Sjogren's Syndrome News

People with primary Sjögren’s syndrome are six times more likely to be deficient in vitamin B12, a study found, supporting the need for screening and treating vitamin B12 deficiency in ... Read more