Sjogren’s Syndrome News

July 29, 2020July 29, 2020

Severe Dryness Symptoms Increase Risk of Cavities, Oral Candida

Severe dryness symptoms increase the risk of developing tooth cavities and having oral Candida infection in people with Sjögren’s syndrome, a new study found. The study, “Sicca Symptoms, Oral Health Conditions, Salivary ... Read more

July 22, 2020July 22, 2020

Australian Partnership to Advance Technology to Treat Sjogren’s

Sjogren's Syndrome News

The University of Queensland’s technology transfer company, UniQuest, will partner with the biotechnology company CSL Limited to develop and commercialize the university’s antigen specific immune tolerance induction (ASITI) technology for ... Read more

July 15, 2020July 15, 2020

Luminary Therapeutics, Case Western Team Up to Develop New CAR T-Cell Therapy

Sjogren's Syndrome News

Luminary Therapeutics will collaborate with researchers at Case Western Reserve University to develop a new form of CAR T-cell therapy that uses the B-cell activating factor (BAFF) target as a ... Read more

July 1, 2020July 6, 2020

Researchers Discover Two Potential Biomarkers for Primary Sjögren’s Syndrome

Sjogren's Syndrome News

A new study has uncovered two potential biomarkers of primary Sjögren’s syndrome (pSS): progranulin (PGRN) and Oxford 40 ligand (OX40L). People with pSS have higher levels of these two proteins compared to healthy volunteers. The study, ... Read more

June 24, 2020June 24, 2020

‘Master Regulator’ Discovery Sheds Light on Autoimmune Diseases Such as Sjogren’s

Sjogren's Syndrome News

Researchers have discovered the mechanisms by which Bcl-6 — a protein that is considered a “master regulator” of the immune system — controls the activity of a subset of immune ... Read more

June 17, 2020June 18, 2020

B-cell Protein May Contribute to Development of Primary Sjogren’s Syndrome

Sjogren's Syndrome News

People with primary Sjögren’s syndrome (pSS) have significantly higher levels of CD72 — a regulatory protein on B-cells, a type of immune cell associated with pSS — than healthy peers, according to a ... Read more

June 3, 2020June 3, 2020

Wize Completes Phase 4 Study of LO2A Eye Drops for Sjögren’s; Results Expected Later This Year

COVID-19 News, Sjogren's Syndrome News

A Phase 4 clinical trial evaluating Wize Pharma‘s LO2A eye drops as a treatment for dry eye symptoms in people with Sjögren’s syndrome has been completed, the company announced. Results from ... Read more

May 20, 2020May 20, 2020

Researchers Shed Light on Genetics Behind Sex-based Vulnerability to Sjögren’s, Other Diseases

COVID-19 News, Sjogren's Syndrome News

Genetic variations in the complement system — a part of the immune response — contribute to differences between men and women in their susceptibility to Sjögren’s syndrome, lupus, and schizophrenia, ... Read more

May 13, 2020May 13, 2020

Research Implicates MicroRNA in Primary Sjögren’s Syndrome Eye Inflammation

Sjogren's Syndrome News

A small RNA molecule may help to drive inflammation in the eyes of people with primary Sjögren’s syndrome (pSS), a new study reports. The findings imply that this molecule, called ... Read more

May 6, 2020May 6, 2020

Damage to Eye Surface Evident in Sjögren Patients, Study Reports

Sjogren's Syndrome News

In addition to dry eyes, people with Sjögren syndrome have damage to the surface of their eyes, and those with most extensive damage have high levels of biomarkers linked to ... Read more

April 29, 2020June 1, 2020

Surge in Telemedicine One ‘Good’ Outcome from COVID-19 Crisis, Doctors Say

COVID-19 News, Sjogren's Syndrome News

While there are few silver linings to the cloud created by COVID-19, the pandemic that has killed tens of thousands, hobbled economies worldwide and drove millions to quarantine in their ... Read more

April 22, 2020April 22, 2020

Bacteria in Mouth May Trigger Inflammation Damaging to Salivary Glands

Sjogren's Syndrome News

Alterations in salivary glands that cause immune cell infiltration in Sjӧgren’s syndrome patients may be triggered by changes in the mouth’s bacterial composition, findings from a recent study suggest. While ... Read more

April 15, 2020April 15, 2020

Vaginal Dryness in Sjögren’s Traced Partly to Blood Vessel Defects

Sjogren's Syndrome News

Vaginal dryness in women with primary Sjögren’s syndrome may be caused by defective blood vessels and an infiltration of immune cells in their vagina and cervix, a new study suggests. The ... Read more

April 8, 2020April 8, 2020

Sjögren’s Symptoms Not Affected by Seasonal Changes, Study Finds

Sjogren's Syndrome News

Seasonal changes do not appear to significantly influence the main symptoms of primary Sjögren’s syndrome — pain, fatigue, and dryness — according to a large study. The study, “Seasonal effect ... Read more

April 1, 2020April 1, 2020

Poor Sleep Linked to Fatigue and Disease Activity in Primary Sjögren’s

Sjogren's Syndrome News

Poor sleep quality is linked to both fatigue and increased disease activity in primary Sjögren’s syndrome patients, a study reported. Its researchers recommend more study into ways that might help patients with ... Read more