Sjogren’s Syndrome News

October 19, 2020October 19, 2020

$3.7M NIH Grant Will Support Research to Pinpoint Genes Associated With Sjögren’s

The National Institute of Arthritis and Musculoskeletal and Skin Diseases, a part of the National Institutes of Health, has awarded a $3.7 million grant to advance studies investigating which genes are ... Read more

October 12, 2020October 12, 2020

Endoscopic Irrigation Brings Long-term Oral Relief to Sjögren’s Patients in Trial

Sjogren's Syndrome News

The use of sialendoscopy, an endoscopic tool to examine and treat the salivary glands, can be used to irrigate the major salivary glands with saline to increase salivation and lessen oral ... Read more

September 30, 2020September 30, 2020

Signaling Molecule IL-38 Can Reduce Inflammation, May Be Therapy Target, Study Finds

Sjogren's Syndrome News

Interleukin-38, an immune signaling molecule known as IL-38, can reduce the inflammatory activity of a type of immune cells involved in primary Sjögren’s syndrome (pSS), and may be a therapeutic ... Read more

September 21, 2020September 21, 2020

Arginase 1 Protein May Protect from Sjögren’s-related Dryness, Mouse Study Suggests

Sjogren's Syndrome News

The arginase 1 protein appears to protect from dryness symptoms associated with Sjögren’s syndrome, potentially by lowering gland inflammation and increasing fluid secretion, a new study in mice indicates. The findings ... Read more

September 14, 2020September 14, 2020

Attention Deficits May Underlie Cognitive Impairment in Neuro‐Sjögren’s, Study Finds

Sjogren's Syndrome News

Attention deficits may underlie the cognitive impairment that impacts a substantial portion of Sjögren’s syndrome patients with neurological symptoms, according to a new study. Such impairment is likely to affect ... Read more

September 9, 2020September 9, 2020

Tumor Markers in Blood May Help Diagnose Lung Disease in Sjögren’s Patients, Study Finds

Sjogren's Syndrome News

The tumor protein CA153 may be a valuable blood biomarker for the early diagnosis and treatment of interstitial lung disease (ILD) in people with primary Sjögren’s syndrome (pSS), a recent study ... Read more

September 2, 2020September 2, 2020

Increased Gene Activity Linked to Immune Cell Malfunction, Study Reveals

Sjogren's Syndrome News

High activity levels in immune-related genes are associated with the malfunction of immune cells isolated from people with primary Sjogren’s syndrome, a small study revealed. Such increased gene activity levels ... Read more

August 19, 2020August 20, 2020

Unexplained Kidney, Neurological Problems, Fever Could Be Sjögren’s

Sjogren's Syndrome News

Primary Sjögren’s syndrome (pSS) should be considered in children with unexplained kidney and neurological symptoms, and unexplained fever, a study suggests. In the study, “Nephrological disorders and neurological involvement in ... Read more

August 12, 2020August 14, 2020

Saliva Levels of IL-6 Protein May Help in Diagnosing Primary Sjögren’s

Sjogren's Syndrome News

Measuring the protein IL-6 in saliva may aid in diagnosing primary Sjogren’s syndrome (pSS), a study reports. The study, “Association of salivary inflammatory biomarkers with primary Sjögren’s syndrome,” was published in ... Read more

July 29, 2020July 29, 2020

Severe Dryness Symptoms Increase Risk of Cavities, Oral Candida

Sjogren's Syndrome News

Severe dryness symptoms increase the risk of developing tooth cavities and having oral Candida infection in people with Sjögren’s syndrome, a new study found. The study, “Sicca Symptoms, Oral Health Conditions, Salivary ... Read more

July 22, 2020July 22, 2020

Australian Partnership to Advance Technology to Treat Sjogren’s

Sjogren's Syndrome News

The University of Queensland’s technology transfer company, UniQuest, will partner with the biotechnology company CSL Limited to develop and commercialize the university’s antigen specific immune tolerance induction (ASITI) technology for ... Read more

July 15, 2020July 15, 2020

Luminary Therapeutics, Case Western Team Up to Develop New CAR T-Cell Therapy

Sjogren's Syndrome News

Luminary Therapeutics will collaborate with researchers at Case Western Reserve University to develop a new form of CAR T-cell therapy that uses the B-cell activating factor (BAFF) target as a ... Read more

July 1, 2020July 6, 2020

Researchers Discover Two Potential Biomarkers for Primary Sjögren’s Syndrome

Sjogren's Syndrome News

A new study has uncovered two potential biomarkers of primary Sjögren’s syndrome (pSS): progranulin (PGRN) and Oxford 40 ligand (OX40L). People with pSS have higher levels of these two proteins compared to healthy volunteers. The study, ... Read more

June 24, 2020June 24, 2020

‘Master Regulator’ Discovery Sheds Light on Autoimmune Diseases Such as Sjogren’s

Sjogren's Syndrome News

Researchers have discovered the mechanisms by which Bcl-6 — a protein that is considered a “master regulator” of the immune system — controls the activity of a subset of immune ... Read more

June 17, 2020June 18, 2020

B-cell Protein May Contribute to Development of Primary Sjogren’s Syndrome

Sjogren's Syndrome News

People with primary Sjögren’s syndrome (pSS) have significantly higher levels of CD72 — a regulatory protein on B-cells, a type of immune cell associated with pSS — than healthy peers, according to a ... Read more