Sjogren’s Syndrome News

June 14, 2022June 15, 2022

Function of Regulatory T-cells Impaired in Women With Sjögren’s: Study

Sjogren's Syndrome News

The function of immune regulatory T-cells (Tregs) — cells that play a key role in dampening the body’s immune response — is impaired in women with Sjögren’s syndrome, a study ... Read more

June 7, 2022June 7, 2022

New Way of Approaching Tear Test May Identify Protein Biomarkers of Sjögren’s

Sjogren's Syndrome News

Researchers have developed a quick, noninvasive way of collecting tear fluid and analyzing the proteins in it — an approach that could eventually be used to identify biomarkers that help ... Read more

May 31, 2022May 31, 2022

Blood Protein Levels May Help ID Hidden Lung Disease in Sjögren’s

Sjogren's Syndrome News

Elevated levels in the blood of the protein Krebs von den Lungen-6 (KL-6) — an indicator of lung inflammation — may help identify interstitial lung disease (ILD) in people with ... Read more

May 24, 2022May 24, 2022

‘Sleep Hormone’ Melatonin Shows Promise in Sjögren’s Mouse Model

Sjogren's Syndrome News

The activity of certain “clock genes” — those involved in the body’s internal clock, or circadian rhythm — is significantly dysregulated in the salivary glands of people with primary Sjögren’s ... Read more

May 17, 2022May 18, 2022

Patients May Be at High Risk for Multiple Cancer Types: Meta-Analysis

Sjogren's Syndrome News

People with Sjögren’s syndrome may be at a higher risk of developing multiple types of cancer, according to a recent meta-analysis of several published studies. The analysis confirms a previously identified ... Read more

May 10, 2022May 10, 2022

3D Tear Duct ‘Mini Organs’ Could Help Advance Research Into Dry Eyes

Sjogren's Syndrome News

A research team in Japan has developed three-dimensional (3D) “mini organs” from human stem cells to model the lacrimal glands, or tear ducts, which are dysfunctional in Sjögren’s syndrome. The ... Read more

May 3, 2022May 3, 2022

Steroid Spinal Injections Found to Ease Woman’s Neuropathic Pain

Sjogren's Syndrome News

Steroid injections into the spine — similar to the epidural injections often given during childbirth — were effective in controlling pain as a result of nerve damage in a 32-year-old ... Read more

April 26, 2022April 26, 2022

Blood Levels of Anti-HMGB1 Antibodies May Help in Diagnosing Sjögren’s

Sjogren's Syndrome News

Levels of antibodies that target the nuclear protein HMGB1 are elevated in the bloodstream of adults with Sjögren’s syndrome, a study reported. Detecting anti-HMGB1 antibodies in the blood may support ... Read more

April 19, 2022April 19, 2022

Chemical Messenger CCL28 May Be Promising Biomarker for Sjögren’s

Sjogren's Syndrome News

Levels of the chemical messenger CCL28 are reduced in the blood of people with primary and secondary Sjögren’s syndrome, and were correlated with oral disease features like dental cavities and ... Read more

April 12, 2022April 12, 2022

Intense Pulsed Light Therapy Eases Sjögren’s Dry Eyes, Study Reports

Sjogren's Syndrome News

Intense pulsed light therapy along with meibomian gland expression (IPL-MGX) significantly eased dry eye symptoms and improved eye health in people with Sjögren’s syndrome, according to a recent study.  “Our ... Read more

April 5, 2022April 6, 2022

NYU Langone Joins NIH’s Quest for Sjögren’s Treatments

Sjogren's Syndrome News

NYU Langone Health is joining with a National Institutes of Health (NIH) sponsored program aimed at understanding disease mechanisms and developing new treatments for autoimmune disorders such as Sjögren’s syndrome. ... Read more

March 29, 2022March 29, 2022

Spotlight on Patients, Their Experiences During Sjögren’s Awareness Month

Sjogren's Syndrome News

This year’s Sjögren’s Awareness Month will focus on patient experiences to share glimpses into the lives of people with Sjögren’s syndrome, a complex disorder that is thought to affect four ... Read more

March 22, 2022March 22, 2022

Retinal Thinning May Help Diagnose Sjögren’s, Imaging Study Shows

Sjogren's Syndrome News

The thickness of the eye’s retina and the density of retinal blood vessels are significantly lower in women with Sjögren’s syndrome than healthy women, an imaging study demonstrated. Retinal thinning, ... Read more

March 15, 2022March 15, 2022

Mental, Physical Health Decline as Symptoms Interrupt Daily Activities: Study

Sjogren's Syndrome News

Fatigue had the biggest impact on daily activities among people with primary Sjögren’s syndrome and was one of a number of symptoms associated with increased anxiety, depression, and physical limitations, according ... Read more

March 8, 2022March 8, 2022

Dry Eye Discomfort Seen as Less Severe by Patients With Sjögren’s

Sjogren's Syndrome News

Dry eye disease is more severe in people with primary Sjögren’s syndrome than in other patients, but their perception of eye discomfort may be altered, according to a recent study. ... Read more