Scleroderma News

May 4, 2021May 4, 2021

Genetic Activity in Skin May Define Stages of Juvenile Localized Scleroderma

Scleroderma News

Distinct profiles of gene activity in skin samples distinguish different disease stages in juvenile localized scleroderma, a study suggests. These profiles did not necessarily match the patients’ clinical subtype or ... Read more

April 29, 2021April 29, 2021

Computer Algorithm Highly Accurate at Detecting PAH in Scleroderma

Scleroderma News

A computer algorithm called DETECT correctly identified all cases of a potentially life-threatening type of high blood pressure in a group of people with scleroderma in a recent study. The algorithm ... Read more

April 27, 2021April 27, 2021

Study Differentiates Gene Activity Between Scleroderma, Lung Cancer

Scleroderma News

Gene activity analysis has revealed similarities and differences between scleroderma and related lung cancer, a study reports. Similarities were related to enhanced immunity and weakened regulation of a cell’s life ... Read more

April 22, 2021April 22, 2021

Stem Cells Can Augment Fat Grafts in Treating Facial Atrophy

Scleroderma News

Treating facial atrophy in localized scleroderma by grafting stem cells from a patient’s own fat tissue appears to be a safe and effective alternative to existing methods, according to a ... Read more

April 20, 2021April 21, 2021

Vasohibin-1 Levels May Serve as Biomarker for Lung, Skin Scarring

Scleroderma News

Higher-than-normal blood levels of the vasohibin-1 protein are associated with a greater risk of interstitial lung disease (ILD) and skin scarring among people with scleroderma, a study suggests. The researchers ... Read more

April 16, 2021April 16, 2021

EveryLife Scholarship Fund Open Until May 7 for Adults With Rare Diseases in US

COVID-19 News, Scleroderma News

The EveryLife Foundation for Rare Diseases is accepting applications for a scholarship program that aims to help adults with a rare disease pursue personal goals through training and education. For a ... Read more

April 15, 2021April 15, 2021

Scleroderma Foundation Awards 8 Grants to Advance Research Priorities

Scleroderma News

The Scleroderma Foundation has awarded eight research grants for projects seeking to advance personalized medicine, lab-grown skin, new therapeutic targets, and more, in the field of scleroderma research. “The proposals ... Read more

April 13, 2021April 13, 2021

Galectin‐10 Blood Levels Linked With Inflammation, Lung Remodeling in Study

Scleroderma News

Low levels of the galectin-10 protein (Gal-10) in scleroderma patients associate with inflammation and vascular changes in the lungs, leading to pulmonary arterial hypertension (PAH). This finding, from a recent study, ... Read more

April 8, 2021April 8, 2021

New Computer Learning Tool 95% Accurate in Screening for SSc

Scleroderma News

Using a laptop, a computer-based machine learning tool was able to distinguish, with 95% accuracy, normal skin images from those collected from people with systemic sclerosis (SSc), a study demonstrated. This ... Read more

April 6, 2021April 6, 2021

Actemra, Given Early to SSc-ILD Patients, Preserves Lung Health, Trial Data Show

Scleroderma News

CT scans show that Actemra (tocilizumab) can prevent lung disease in patients with systemic scleroderma if detected early enough, an analysis of Phase 3 trial data reported.  These findings support ... Read more

April 1, 2021April 1, 2021

Cost of Rare Diseases in US? Nearly $1 Trillion in 2019, EveryLife Foundation Finds

Scleroderma News

As anyone affected by a rare disease knows, treating the illness while trying to go about everyday life is an expensive undertaking.  But exactly how expensive — in terms of ... Read more

March 30, 2021March 30, 2021

Applications Sought for Foundation Scholarships

COVID-19 News, Scleroderma News

The Anna Belle Carter Memorial Foundation (ABCMF) is offering scholarships to students living with scleroderma and their siblings who remain under the care of their parents and guardians. Recipients can ... Read more

March 25, 2021March 25, 2021

Pain, Poor Sleep Can Lead to Lower Quality of Life for Patients

Scleroderma News

Chronic pain and impairment of the autonomic nervous system — which controls internal organs and regulates body processes like heart rate, blood pressure, digestion, and respiration — affect sleep and ... Read more

March 23, 2021March 23, 2021

CAN10 Shows Promise in Early Studies, Supporting Planned Clinical Trial

Scleroderma News

CAN10, — Cantargia’s experimental therapy for scleroderma and myocarditis, or inflammation of the heart muscle — appears safe and effective at reducing inflammation and myocarditis in preclinical studies. The findings ... Read more

March 18, 2021March 18, 2021

C21 Improved Blood Flow in People With Raynaud’s Secondary to Scleroderma

COVID-19 News, Scleroderma News

Oral treatment with C21 restored hand temperature by improving blood flow  in people with Raynaud’s phenomenon secondary to scleroderma, top-line data from a Phase 2 clinical trial show. “The results of ... Read more