Scleroderma News

January 13, 2022January 13, 2022

National Scleroderma Foundation Hopes New Name Will Increase Reach

Scleroderma News

The Scleroderma Foundation is relaunching itself under a new name, the National Scleroderma Foundation, intending to reach and educate a larger audience and connect more of those affected by scleroderma ... Read more

January 11, 2022January 11, 2022

CoronaVac COVID-19 Vaccine Less Effective in Scleroderma in Brazil

COVID-19 News, Scleroderma News

People with systemic sclerosis (SSc) in Brazil had a weaker immune response to the CoronaVac COVID-19 vaccine than did healthy individuals, a study discovered. The findings also showed that treatment ... Read more

January 6, 2022January 6, 2022

New Risk Factors for Diastolic Dysfunction Identified in Study

Scleroderma News

Several risk factors for diastolic dysfunction (DD), the heart’s inability to fill with blood properly after it beats, were identified in people with systemic sclerosis (SSc) in a recent study. ... Read more

January 4, 2022January 4, 2022

CAN10 Counters Scleroderma Development in Preclinical Study

Scleroderma News

Cantargia’s investigational antibody treatment, CAN10, showed promise in an animal model of systemic sclerosis (or scleroderma), normalizing several biological indicators of disease and counteracting disease development in the skin and ... Read more

December 30, 2021December 30, 2021

Prepare to Light Up Buildings for Rare Disease Day 2022

COVID-19 News, Scleroderma News

The National Organization for Rare Disorders (NORD) asks Americans to plan ahead to participate in the Light Up for Rare campaign to raise awareness of rare diseases. NORD is the ... Read more

December 28, 2021December 28, 2021

Sine Sclerosis Linked to Better Survival Than Limited, Diffuse Types

Scleroderma News

People with sine sclerosis — a rare form of scleroderma without skin involvement — have better survival than those with limited and diffuse scleroderma, according to a retrospective study of ... Read more

December 23, 2021December 23, 2021

Oxygen-ozone Therapy Effective for Hard-to-treat Finger, Toe Ulcers

Scleroderma News

Targeted oxygen-ozone therapy effectively reduced digital ulcers — open sores on the fingers or toes — that had proven resistant to standard treatment in people with systemic sclerosis (SSc), a ... Read more

December 21, 2021December 22, 2021

Nonwhite Patients More at Risk for Restrictive Lung Disease, Study Finds

Scleroderma News

Patients with scleroderma are more likely to develop restrictive lung disease (RLD) — a precursor to interstitial lung disease (ILD) — if they are nonwhite, according to a multicenter U.S. ... Read more

December 16, 2021December 16, 2021

Income, Education May Affect How Patients View Their Capabilities

Scleroderma News

Among people with systemic scleroderma, education and income are major determinants of perceived functional ability, a new study indicates. Findings also point to skin involvement and age as substantial determinants ... Read more

December 14, 2021December 14, 2021

Phase 2 Trial of PRA023 in SSc-ILD Patients Planned for Next Year

Scleroderma News

Prometheus Biosciences is planning a clinical trial of its investigational anti-inflammatory and antifibrotic medication PRA023 in people with systemic scleroderma-associated interstitial lung disease (SSc-ILD), a form of scleroderma characterized by ... Read more

December 9, 2021December 9, 2021

Scleroderma Renal Crisis More Common in Blacks, Study Finds

Scleroderma News

Scleroderma renal crisis (SRC), a rare and severe manifestation of systemic scleroderma, is disproportionately common in Blacks, a new study reports. “Black race was independently associated with a higher risk ... Read more

December 7, 2021December 7, 2021

Low Oxygen in Muscles Linked to Poor Exercise Capacity in SSc Patients

Scleroderma News

Poor oxygenation in skeletal muscles — those used in voluntary movements — contributes to impaired exercise capacity in people with scleroderma, a study suggests. The study, “Reduced exercise capacity in ... Read more

December 2, 2021December 2, 2021

Trial Testing FCR001 for Severe Scleroderma Underway in Michigan

Scleroderma News

Talaris Therapeutics has launched a Phase 2 clinical trial to test its treatment candidate FCR001 for people with diffuse cutaneous systemic sclerosis (dcSSc), a severe form of scleroderma. The trial, ... Read more

November 30, 2021November 30, 2021

Rates of SSc, Raynaud’s Likely Higher Among Post-9/11 Veterans

Scleroderma News

A higher rate of systemic sclerosis (SSc), very early diagnosis of systemic sclerosis (VEDOSS), and Raynaud’s phenomenon is evident among U.S. military veterans deployed in support of post-9/11 operations, compared ... Read more

November 23, 2021November 23, 2021

Blood Proteins Profiles May Serve as Biomarkers of Scleroderma Severity

Scleroderma News

Distinct levels of proteins in the bloodstream of scleroderma patients matched altered gene activity in their skin, a large-scale molecular analysis showed. Researchers said these blood proteins could prove to ... Read more