Pulmonary Hypertension News

May 29, 2020May 29, 2020

Epigenetic Changes May Boost PAH Development, Study Reports

Changes in the epigenetic profile — a collection of marks that turn genes on and off — of pulmonary arterial endothelial cells from people with pulmonary arterial hypertension (PAH) may ... Read more

May 27, 2020May 27, 2020

Kalytera to Acquire R-107, Potential Liquid Nitric Oxide Treatment for PAH

COVID-19 News, Pulmonary Hypertension News

Kalytera Therapeutics intends to acquire Salzman Group, a company developing R-107 — a liquid form of nitric oxide — to possibly treat pulmonary arterial hypertension (PAH), lung disease associated with COVID-19, and other lung ... Read more

May 22, 2020May 26, 2020

Nicotine Inhaled Often, as with E-cigarette Use, Linked to PH in Mice

Pulmonary Hypertension News

Chronic inhalation of nicotine, the addictive component of all tobacco products, is enough to trigger changes in pulmonary arteries and in the heart’s right chamber that can cause pulmonary hypertension ... Read more

May 20, 2020May 20, 2020

Study Reveals How Sotatercept Works in PAH Rat Model, Supporting Its Potential for Patients

Pulmonary Hypertension News

Newly published research has detailed the underlying biochemical process behind Acceleron Pharma’s investigational therapy sotatercept (ACE-011) for the potential treatment of people with pulmonary arterial hypertension (PAH). The findings, in ... Read more

May 15, 2020May 15, 2020

Obesity Linked to Lower Risk of Mortality in PH Patients, Study Finds

Pulmonary Hypertension News

Obesity is linked to a lower risk of mortality in patients with pulmonary hypertension (PH), particularly among those with precapillary PH, a study found. The study, “Obesity Is Associated With ... Read more

May 13, 2020May 13, 2020

INOmax Use Aids Premature Babies with PH, Phase 4 Study Shows

COVID-19 News, Pulmonary Hypertension News

Mallinckrodt Pharmaceuticals’ INOmax (nitric oxide) gas improves oxygenation in premature newborns with pulmonary hypertension (PH) at least as effectively as it does in term and near-term babies, data from a ... Read more

May 11, 2020May 11, 2020

At-home System of Inhaled Nitric Oxide Treats PAH Patient Infected With COVID-19

COVID-19 News, Pulmonary Hypertension News

At-home treatment with inhaled nitric oxide through Genosyl, a tankless delivery system, was used successfully to manage pulmonary arterial hypertension (PAH) complicated by COVID-19 in a patient, according to a case ... Read more

May 8, 2020May 8, 2020

EMA Grants Priority Medicines Designation to Sotatercept for PAH

Pulmonary Hypertension News

The European Medicines Agency (EMA) has granted priority medicines (PRIME) designation to investigational therapy sotatercept (ACE-011) for the treatment of patients with pulmonary arterial hypertension (PAH). This designation is given ... Read more

May 6, 2020May 6, 2020

Opsumit Can Ease Strain on Right Ventricle and PAH Severity, Trial Shows

Pulmonary Hypertension News

When given alone or in combination with other therapies, Opsumit (macitentan) leads to clinically meaningful improvements in right heart function in people with pulmonary arterial hypertension (PAH), according to data ... Read more

May 4, 2020May 5, 2020

PAH Trials Pausing Enrollment for COVID-19, United Therapeutic Says

COVID-19 News, Pulmonary Hypertension News

United Therapeutics has temporarily stopped enrolling patients in ongoing clinical trials of treprostinil-based therapies for pulmonary arterial hypertension (PAH) amid the COVID-19 pandemic, the company announced. Treprostinil is a man-made version of the hormone prostacyclin, ... Read more

May 4, 2020May 4, 2020

Dealing with the Fear of Losing Independence

Pulmonary Hypertension News

One of the hardest things about the diagnosis of a progressive illness is grappling with how your disease will affect your future independence. It can be scary and painful to ... Read more

May 4, 2020May 4, 2020

Can I Have a Bit of Normalcy Without Fear?

Pulmonary Hypertension News

“I have watched fear change us. I have watched fear ride roughshod over our families, organizations, and communities.” – Brené Brown, “Braving The Wilderness.” In the above quote, lecturer Brené ... Read more

May 4, 2020May 4, 2020

The Power of Words

Pulmonary Hypertension News

Lately, I have been reflecting on the power of words. It started one sleepless night, as I wondered how often I have thought or spoken the words pulmonary hypertension since my ... Read more

May 1, 2020May 1, 2020

Expressing My Fears Gives Me a Sense of Freedom

Pulmonary Hypertension News

A few years ago, I thought that talking openly about my fears and worries was a sign of weakness. I convinced myself that being strong meant putting on my bravest ... Read more

May 1, 2020May 1, 2020

LIQ861, Inhaled Form of Treprostinil, Fares Well in Phase 3 Trial for PAH

Pulmonary Hypertension News

LIQ861, Liquidia Technology‘s investigational inhaled formulation of treprostinil, is safe and well-tolerated in patients with pulmonary arterial hypertension (PAH), according to final results from a Phase 3 clinical trial. The ... Read more