Pulmonary Fibrosis News

October 19, 2021October 19, 2021

Facility Inspection Issue Stalls FDA Approval of Tyvaso DPI for PH-ILD

An open inspection issue at a third-party testing facility has put on hold United Therapeutics’ application seeking the approval of Tyvaso DPI, an investigational dry powder inhaled formulation of treprostinil for ... Read more

October 18, 2021October 18, 2021

FSU Researcher Awarded $1.8M by NIH to Investigate Fibrotic Process

Pulmonary Fibrosis News

Research examining the role that protein-RNA interactions play in promoting pulmonary fibrosis (PF) and other related conditions is being accelerated by a $1.8 million grant from the National Institutes of ... Read more

October 15, 2021October 15, 2021

Envisia IPF Diagnostic Tool Increases Accuracy, Doctor’s Confidence

COVID-19 News, Pulmonary Fibrosis News

A new diagnostic tool, the Envisia Genomic Classifier, can help make doctors more confident and accurate in diagnosing idiopathic pulmonary fibrosis (IPF), a new survey suggests. Using the Envisa tool, ... Read more

October 13, 2021October 13, 2021

Rare Disease Diversity Coalition Awards $600K to Combat Disparities

COVID-19 News, Pulmonary Fibrosis News

The Rare Disease Diversity Coalition (RDDC) awarded $600,000 in grants to ease the disparities faced by rare disease patients of color. These Impact Rare Disease Solution grants will go five RDDC ... Read more

October 13, 2021October 13, 2021

RXC007 for IPF Showing Favorable Safety in Ongoing Phase 1 Trial

Pulmonary Fibrosis News

RXC007, an investigational oral therapy for idiopathic pulmonary fibrosis (IPF), is showing favorable safety and pharmacological properties in an ongoing Phase 1 trial in healthy volunteers. The experimental therapy being developed ... Read more

October 12, 2021October 12, 2021

IPF Hospitalizations Linked to 8 Times Higher Mortality Risk

Pulmonary Fibrosis News

People with idiopathic pulmonary fibrosis (IPF) have an eight times higher risk of mortality during hospitalizations or within three months of being discharged than outside this time window, a U.S. ... Read more

October 11, 2021October 11, 2021

N115 Nasal Spray Found to Improve Lung Function in PF Patients

COVID-19 News, Pulmonary Fibrosis News

Treatment with N115, EmphyCorp’s non-steroidal nasal spray, led to statistically and clinically significant improvements across all lung function parameters in patients with pulmonary fibrosis (PF) participating in a Phase 3 trial, ... Read more

October 8, 2021October 8, 2021

Observational Study of PF Drivers Enrolling People With Family History

Pulmonary Fibrosis News

An observational study is hoping to identify early drivers of pulmonary fibrosis (PF) in individuals with a family history of PF, to better understand the molecular mechanisms that underlie the disease ... Read more

October 7, 2021October 7, 2021

‘Rare’ Documentary in Kickstarter Campaign to Raise $45K by Oct. 28

Pulmonary Fibrosis News

A crowdfunding campaign aims to raise $45,000 to support “Rare,” a documentary film featuring the struggles and achievements of people living with rare diseases and their families. Sweis Entertainment and ... Read more

October 6, 2021October 6, 2021

Family History of Short Telomeres – Chromosome ‘Caps’ – Tied to PF Risk

Pulmonary Fibrosis News

People with a familial history of short telomere syndrome (STS) — a disorder involving shortened telomeres, or chromosome “caps” — may be at an increased risk of developing pulmonary fibrosis, ... Read more

October 5, 2021October 5, 2021

Major Air Pollutants Appear to Raise Risk of Acute Exacerbations in IPF

Pulmonary Fibrosis News

Long-term exposure to air pollutants — nitrogen dioxide, ozone, and fine particle matter — appears to greatly raise the risk of acute exacerbations, or sudden bouts of symptom worsening, in people ... Read more

October 4, 2021October 4, 2021

DSP Gene Variant May Aid Survival in IPF, Guide Esbriet or Ofev Use

Pulmonary Fibrosis News

Certain genetic variants appear to lead to better survival in people with idiopathic pulmonary fibrosis (IPF) who are on anti-fibrotics, suggesting that genetic testing may help to select patients for ... Read more

October 1, 2021October 1, 2021

New Data-sharing Program Aims to Speed Innovation in Rare Diseases

Pulmonary Fibrosis News

A new U.S. initiative called Rare Disease Cures Accelerator–Data and Analytics Platform — dubbed RDCA–DAP — aims to accelerate treatment innovation across rare diseases by sharing existing patient data and ... Read more

October 1, 2021October 1, 2021

Study Findings Support Furtherance of GED-0507 for IPF

Pulmonary Fibrosis News

GED-0507, Nogra Pharma’s experimental therapy, significantly reduced the levels of pro-inflammatory and pro-scarring molecules, while suppressing the maturation of myofibroblasts — the main drivers of lung scarring (fibrosis) — to ... Read more

September 29, 2021September 29, 2021

Tony Award Recognizes Actress for Work as PF Advocate

Pulmonary Fibrosis News

Julie Halston, a Broadway theater veteran and comedian, has received the 2020 Isabelle Stevenson Tony Award for her longtime volunteer efforts for the Pulmonary Fibrosis Foundation (PFF). Halston, who is ... Read more