Pulmonary Fibrosis News

July 10, 2020July 10, 2020

World’s First Single-cell Sequencing Atlas Available for Drug Discovery in IPF

Pulmonary Fibrosis News

IPF Cell Atlas, the world’s first single-cell sequencing atlas for idiopathic pulmonary fibrosis (IPF), is now available to the public to advance research into new treatments for the condition. This ... Read more

July 8, 2020July 8, 2020

Algernon Begins Patient Screening for Phase 2 Trial of NP-120 for IPF, Chronic Cough

COVID-19 News, Pulmonary Fibrosis News

Algernon Pharmaceuticals has begun screening patients for its Phase 2 clinical trial investigating its repurposed compound NP-120 (ifenprodil) for the treatment of idiopathic pulmonary fibrosis (IPF) and associated chronic cough. The study ... Read more

July 7, 2020July 7, 2020

Low Testosterone Levels Linked to Chromosome Damage in Men With IPF

Pulmonary Fibrosis News

The protective tips of chromosomes, called telomeres, are shorter in men with idiopathic pulmonary fibrosis (IPF) than age-matched peers, and these changes seem to be linked to lower blood levels ... Read more

July 6, 2020July 6, 2020

IPF Hospitalizations, Mortality Rate Seen to Drop in US from 2006-16

Pulmonary Fibrosis News

Rates of hospitalization and in-hospital mortality dropped significantly for people with idiopathic pulmonary fibrosis (IPF) in the U.S. between 2006 and 2016, and hospitalizations were most common in colder months, ... Read more

July 1, 2020July 2, 2020

Single Lung Transplants Increase Lung Cancer Risk

Pulmonary Fibrosis News

Single lung transplant patients with idiopathic pulmonary fibrosis (IPF) have a higher risk of developing lung cancer, according to a recent study — and these cancers are more likely to ... Read more

June 30, 2020June 30, 2020

Transplanting a Type of Lung Cells Halts Fibrosis in IPF Rat Model

Pulmonary Fibrosis News

A cell therapy approach based on transplanting a type of lung cells called type II alveolar cells halted scarring (fibrosis) in a rat model of idiopathic pulmonary fibrosis (IPF) with established ... Read more

June 29, 2020June 29, 2020

Thrombomodulin May Improve Short-term Survival in IPF Acute Exacerbations, Review Says

Pulmonary Fibrosis News

Treating acute exacerbations with the protein thrombomodulin (ART-123) in idiopathic pulmonary fibrosis (IPF) patients may be associated with short-term survival benefits, a review analysis reports. However, larger studies are needed ... Read more

June 26, 2020June 29, 2020

Early Data Support Ability of MicroRNA Mimic, MRG-229, to Treat IPF

Pulmonary Fibrosis News

New preclinical data support MRG-229, an investigative next-generation treatment for idiopathic pulmonary fibrosis (IPF), as safe and effective, miRagen reported. “We believe this body of evidence supports further development of MRG-229 as a potentially ... Read more

June 24, 2020June 24, 2020

‘Breathless Ballad Challenge’ Welcomes Would-be Songwriters

Pulmonary Fibrosis News

Former New York Yankees center fielder and Latin Grammy nominee Bernie Williams is helping to raise awareness of idiopathic pulmonary fibrosis (IPF), the disease took his father’s life, as part of Boehringer Ingelheim’s national ... Read more

June 23, 2020June 23, 2020

Artificial Stone Work in Homes Linked to Rising Cases of Silicosis, PF

Pulmonary Fibrosis News

Pulmonary fibrosis (PF) that results from inhaling silica dust is rebounding in wealthier counties after years of decline, due to a  rising demand for artificial stone in home construction and ... Read more

June 22, 2020June 22, 2020

Protein Called esRAGE May Be Linked to IPF Progression

Pulmonary Fibrosis News

Low levels of a protein called esRAGE, present in the blood and lungs of people with idiopathic pulmonary fibrosis (IPF), are associated with a poorer prognosis and lower survival rates, ... Read more

June 17, 2020June 17, 2020

Patient-reported Tests Can Predict Mortality, Lung Transplant Risk, Study Says

Pulmonary Fibrosis News

How idiopathic pulmonary fibrosis (IPF) patients assess their own symptoms and physical capacity predicts, to some degree, their risk of dying or of needing a lung transplant, according to a ... Read more

June 16, 2020June 16, 2020

Envisia Genomic Test Increases Confidence of IPF Diagnosis

Pulmonary Fibrosis News

Veracyte’s Envisia Genomic Classifier, the first commercially available genomic test to help diagnose idiopathic pulmonary fibrosis (IPF), can help physicians identify the disease in patients where other tests have been ... Read more

June 15, 2020June 15, 2020

Galapagos, e-therapeutics Partner to Identify Compounds to Treat Fibrotic Diseases

Pulmonary Fibrosis News

Galapagos and e-therapeutics are partnering to investigate mechanisms involved in idiopathic pulmonary fibrosis (IPF) and other fibrotic conditions and to select potential therapeutic candidates. The collaboration will combine Galapagos’ extensive ... Read more

June 12, 2020June 12, 2020

Membrane-repair Protein May Be IPF Treatment Target, Early Study Finds

Pulmonary Fibrosis News

Increasing the levels of a membrane-repair protein called tripartite motif containing 72 (TRIM72) protected against lung cell injury and lessened lung fibrosis in a mouse model of idiopathic pulmonary fibrosis (IPF). ... Read more