Prader-Willi News

January 13, 2022January 13, 2022

Abnormal Brain Activity Found in PWS Patients When They See Food

Prader-Willi News

In people with Prader-Willi syndrome (PWS), certain parts of the brain associated with decision-making and reward processing are less active in response to the sight of food, a study has ... Read more

January 11, 2022January 11, 2022

Interviews Reveal Struggles With Hunger, Anxiety for People With PWS

Prader-Willi News

Adolescents and adults with Prader-Willi syndrome (PWS) say they struggle with constant hunger and the urge to seek food, according to an interview-based study. Participants experienced difficulties with anxiety, behavioral ... Read more

January 6, 2022January 6, 2022

PWS Families Favor Team Clinic Over Current Care, Small Study Suggests

Prader-Willi News

Pediatric multidisciplinary team clinics for Prader-Willi syndrome (PWS) offer an improved service that supports the diverse and challenging needs of children with the disease, according to a small parental interview-based ... Read more

January 4, 2022January 4, 2022

Obese PWS Patients at Increased Risk of Type 2 Diabetes as Adults

Prader-Willi News

Patients with Prader-Willi syndrome (PWS) are at increased risk of developing type 2 diabetes mellitus as they transition into adulthood, particularly if they are severely obese and/or undergoing rapid weight ... Read more

December 30, 2021December 30, 2021

Global Phase 2b Trial Launching of Tesomet in Easing Hyperphagia

Prader-Willi News

Saniona is launching a Phase 2b clinical trial of Tesomet to evaluate its potential in lessening the uncontrollable hunger of people with Prader-Willi syndrome (PWS). “The initiation of this Phase 2b ... Read more

December 28, 2021December 28, 2021

Prepare to Light Up Buildings for Rare Disease Day 2022

COVID-19 News, Prader-Willi News

The National Organization for Rare Disorders (NORD) asks Americans to plan ahead to participate in the Light Up for Rare campaign to raise awareness of rare diseases. NORD is the ... Read more

December 23, 2021December 23, 2021

2 Boys With PWS Develop Respiratory Failure After Scoliosis Surgery

Prader-Willi News

Two boys with Prader-Willi syndrome (PWS) developed respiratory failure — a condition in which the oxygen level in the blood becomes too low — after surgery to correct scoliosis (a ... Read more

December 21, 2021December 21, 2021

NAC Has Limitations in Easing Patients’ Skin-picking Behavior, Small Study Finds

Prader-Willi News

N-Acetylcysteine (NAC) may help to reduce skin-picking behavior in some people with Prader-Willi syndrome (PWS), but many patients do not benefit from NAC treatment, a new study found. “NAC should ... Read more

December 16, 2021December 16, 2021

Cerebellum Plays Role in Stimulating Appetite in PWS, Study Discovers

Prader-Willi News

MRI brain scans of Prader-Willi syndrome (PWS) patients unexpectedly revealed nerve cells in the cerebellum of the brain activated by food cues that promote appetite, a study demonstrated. The findings ... Read more

December 14, 2021December 14, 2021

Clinical Trials Sought to Test GLP1-RA, Which May Promote Weight Loss

Prader-Willi News

A class of medications called GLP-1 receptor agonists (GLP1-RA) may help reduce appetite and promote weight loss for people with Prader-Willi syndrome (PWS), according to a review paper. The paper’s ... Read more

December 9, 2021December 9, 2021

Research on Molecular Changes in PWS Sheds New Light on High Autism Risk

Prader-Willi News

The activity of nine genes located outside the so-called PWS locus — a region containing genes in Prader-Willi syndrome (PWS) that are lost or have defects — is significantly altered ... Read more

December 7, 2021December 7, 2021

Behavioral Training Study Seeks Caregivers of PWS Children

Prader-Willi News

A new study is looking for participants to assess the impact of a behavioral training program for caregivers of children with Prader-Willi syndrome (PWS). The training program, led by Kasey ... Read more

December 2, 2021December 2, 2021

Overeating Behavior Can Lead to Risks Unrelated to Obesity: Review

COVID-19 News, Prader-Willi News

Excessive eating in Prader-Willi syndrome (PWS) increases the risk of mortality not only by making patients prone to obesity and its associated health problems, but also by raising the risk ... Read more

November 30, 2021November 30, 2021

Obesity May Cause ‘Subtle’ Heart Changes Starting in Early Adulthood

Prader-Willi News

Subtle heart changes in people with Prader–Willi syndrome (PWS) may begin relatively early in adulthood, and being overweight may be related to these cardiovascular abnormalities, a small study reported. “We ... Read more

November 23, 2021November 23, 2021

‘Significantly’ Lower Levels of Growth Hormone IGF-1 Found in PWS Infants

Prader-Willi News

Infants and toddlers with Prader-Willi syndrome (PWS) have significantly lower blood levels of insulin-like growth factor 1 or IGF-1 — indicative of growth hormone (GH) deficiency — than their healthy ... Read more