Myasthenia Gravis News

August 7, 2020August 10, 2020

COVID-19 May Complicate Neuromuscular Conditions Such as MG

A review of studies related to COVID-19 and neuromuscular disorders such as myasthenia gravis (MG) found that the novel coronavirus can exacerbate symptoms in patients, including those on immune-related therapies. ... Read more

August 4, 2020August 4, 2020

Protein May Be Biomarker to Help Identify Difficult-to-diagnose MG

Myasthenia Gravis News

High levels of kappa free light chain — a protein that makes up a portion of immunoglobulins (antibodies) — in the bloodstream may indicate the presence of myasthenia gravis (MG) ... Read more

July 31, 2020August 3, 2020

Argenx Plans FDA Submission of Efgartigimod by Year’s End

Myasthenia Gravis News

Argenx is planning to submit an application to the U.S. Food and Drug Administration (FDA) by the end of this year for its lead candidate, efgartigimod (ARGX-113), for the treatment ... Read more

July 28, 2020July 28, 2020

Case Supports Soliris as Promising Treatment for Thymoma-associated MG

Myasthenia Gravis News

Soliris (eculizumab) may be a promising treatment option for patients with refractory myasthenia gravis (MG) associated with a tumor in the thymus gland, a case report suggests. The case report ... Read more

July 24, 2020July 24, 2020

Long-term Soliris Therapy Leads to Sustained Muscle Strength Improvement, Studies Show

Myasthenia Gravis News

Treatment with Soliris (eculizumab) led to rapid and sustained improvements in muscle strength and the ability to perform daily activities in people with refractory generalized myasthenia gravis (gMG) who have ... Read more

July 21, 2020July 21, 2020

Stress and Depression Linked With Relapses in MG Patients

Myasthenia Gravis News

Stress and depression are associated with higher relapse rates in people with myasthenia gravis (MG), according to a recent study. Attention to evidence of either disorder is important for proper ... Read more

July 17, 2020July 17, 2020

Dutch Trial to Test NMD670 Oral Treatment Candidate

Myasthenia Gravis News

NMD Pharma is launching a Phase 1/2a trial in the Netherlands to evaluate for the first time NMD670, an oral treatment candidate for people with myasthenia gravis (MG). The study ... Read more

July 14, 2020July 14, 2020

Case Report Describes Late-onset MG in Man Treated for Multiple Myeloma

Myasthenia Gravis News

A 60-year-old man being treated for multiple myeloma was found to have myasthenia gravis (MG) caused by antibodies against muscle-specific tyrosine kinase (MuSK), a study reports. This unusual case indicates ... Read more

July 10, 2020July 10, 2020

More Severe Disease in MG Patients with LRP4 and Agrin Autoantibodies

Myasthenia Gravis News

People with myasthenia gravis who have autoantibodies targeting the proteins LRP4 and agrin have more severe disease compared to patients without those antibodies, a study has found. However, regardless of ... Read more

July 7, 2020July 8, 2020

3P Biopharmaceuticals and Toleranzia Advance Partnership to Develop TOL2 for MG

Myasthenia Gravis News

3P Biopharmaceuticals and Toleranzia are continuing their partnership to develop Toleranzia’s potential therapy candidate, TOL2, for people living with myasthenia gravis (MG). “Currently there are enormous opportunities offered by biotechnology as ... Read more

June 30, 2020June 30, 2020

Immunovant Prepares to Launch Phase 3 Trial of IMVT-1401 in MG Patients

COVID-19 News, Myasthenia Gravis News

Immunovant is preparing to launch a Phase 3 trial of its investigational candidate IMVT-1401 in patients with myasthenia gravis (MG); it may lead to the treatment’s approval for this indication, pending ... Read more

June 26, 2020June 26, 2020

Rituximab Effective for People With Refractory MG, Study Finds

Myasthenia Gravis News

People with myasthenia gravis (MG) who fail to respond to standard therapies or are dependent on steroid use can safely and effectively be treated with rituximab, an immune modulating medicine, a ... Read more

June 23, 2020June 23, 2020

Mitochondria Defects in Immune Cells May Cause MG, Study Says

Myasthenia Gravis News

Defects in mitophagy — the process that degrades defective mitochondria, the cell compartments responsible for producing energy — in certain types of immune cells may cause myasthenia gravis (MG), a ... Read more

June 22, 2020July 23, 2020

Alexion Charitable Foundation Giving $1.1M to Assist Rare Disease Community During Pandemic

COVID-19 News, Myasthenia Gravis News

The Alexion Charitable Foundation has awarded $1.1 million in grants to programs that support those with rare diseases during the COVID-19 pandemic, the organization recently announced. The grants will support ... Read more

June 19, 2020June 19, 2020

Rituximab More Beneficial if Given to gMG Patients Early, Study Finds

Myasthenia Gravis News

Rituximab seems to be more effective in newly-diagnosed patients with generalized myasthenia gravis (gMG), compared to people at more advanced stages of the disease, a study has found. Investigators also ... Read more