Myasthenia Gravis News

October 23, 2020October 23, 2020

gMG Symptoms May Worsen Severely After Stopping Soliris, Case Study Reports

Myasthenia Gravis News

A Japanese man with generalized myasthenia gravis (gMG) experienced a severe worsening of symptoms after discontinuing treatment with Soliris (eculizumab), a case study reported.  Titled “Severe worsening of myasthenic symptoms ... Read more

October 20, 2020October 20, 2020

Activating Bile Acid Receptor May Be Therapy Target for MG, Study Reports

Myasthenia Gravis News

Activating the bile acid receptor TGR5 was found to reduce the number of immune cells that secrete proinflammatory proteins, suggesting that this receptor may be a therapeutic target for people ... Read more

October 16, 2020October 16, 2020

First Case of Ocular MG Following COVID-19 Described in Report

COVID-19 News, Myasthenia Gravis News

The first published case of a person developing ocular myasthenia gravis (MG) secondary to COVID-19 was described in a new report. The patient, a 65-year-old woman with a medical history ... Read more

October 13, 2020October 13, 2020

1st Participant Dosed in Phase 1/2a Trial Testing Potential MG Therapy NMD670

Myasthenia Gravis News

The first participant has been dosed in a Phase 1/2a trial evaluating NMD670, NMD Pharma‘s investigational therapy for myasthenia gravis (MG). “I am pleased to announce that our lead program ... Read more

October 9, 2020October 9, 2020

New Phase 3 Trial Data Support Efficacy of Efgartigimod for Generalized MG

Myasthenia Gravis News

Treatment with Argenx‘s investigational therapy efgartigimod leads to significant and early reductions in the severity of generalized myasthenia gravis (gMG), regardless of the presence of antibodies against acetylcholine receptor (AChR), ... Read more

October 6, 2020October 6, 2020

Depression, Prednisone Use Linked to Cognitive Problems in Patients

Myasthenia Gravis News

Tasks involving memory can be difficult for people with myasthenia gravis (MG) due to depression and the use of glucocorticosteroids, a study from Brazil found. The study, “Cognitive performance in ... Read more

October 2, 2020October 2, 2020

Dosing Begins in Phase 2 Trial Testing Batoclimab for Myasthenia Gravis

Myasthenia Gravis News

A Phase 2 clinical trial of Harbour BioMed‘s investigational therapy batoclimab, also known as HBM9161, for myasthenia gravis (MG), has started dosing patients, the company said in a press release. ... Read more

September 29, 2020September 29, 2020

Both IVIG and SCIG Effective as Maintenance Therapy in MG, Study Finds

Myasthenia Gravis News

For the first time, a real-world study comparing the effects of long-term intravenous (IVIG) and subcutaneous immunoglobulin (SCIG) maintenance therapy in adults with generalized myasthenia gravis (gMG) showed reduced impairments, ... Read more

September 25, 2020September 25, 2020

Possible Genetic Component to MG Found in Large-scale North American Analysis

Myasthenia Gravis News

A large-scale analysis of people with myasthenia gravis (MG) in North America revealed a higher prevalence of MG and other autoimmune disorders among their families, suggesting there may be a ... Read more

September 22, 2020September 22, 2020

Early Anticholinesterase Use May Benefit MG Patients With Thymus Tumor

Myasthenia Gravis News

Among people with myasthenia gravis (MG) and thymoma — a tumor of the thymus — being male and having more severe disease, advanced thymoma, or post-surgery complications predict poorer outcomes, a study ... Read more

September 18, 2020September 18, 2020

Changed Levels of Complement-associated Proteins Implicated in Generalized MG, Study Suggests

Myasthenia Gravis News

Altered levels of immune proteins associated with the complement system may be implicated in generalized myasthenia gravis (MG), a new study suggests. The study, “Changes in serum complements and their ... Read more

September 15, 2020September 16, 2020

Lower Quality of Life in Women Linked to Coexisting Diseases, Chinese Study Finds

Myasthenia Gravis News

Women with myasthenia gravis (MG) have a diminished quality of life compared with male patients, and are particularly affected by the number of additional diseases (comorbidities) they experience, a new study ... Read more

September 11, 2020September 11, 2020

Older MG Patients on IVIG May Have Higher Risk of Coronary Spastic Angina

Myasthenia Gravis News

Older patients with myasthenia gravis (MG) who receive treatment with intravenous immunoglobulin (IVIG) may be at a higher risk of developing coronary spastic angina, known as CSA, according to a ... Read more

September 8, 2020September 8, 2020

Levels of Inflammatory Molecule IL-36 Gamma Reflect MG Severity, Study Finds

Myasthenia Gravis News

The inflammatory molecule interleukin-36 (IL-36) gamma is associated with the severity of myasthenia gravis (MG), and may participate in disease processes by activating certain immune cells, a recent study suggests. ... Read more

September 4, 2020September 4, 2020

Patient with Three MG Antibodies Described in Case Report

Myasthenia Gravis News

A patient with three different types of myasthenia gravis (MG)-associated antibodies was described in a recent case report. The report, “Anti-MuSK positive myasthenia gravis with anti-Lrp4 and anti-titin antibodies,” was ... Read more