Lambert-Eaton News

July 2, 2020July 6, 2020

Scientists Validate New Tool for Estimating Cancer Risk in LEMS Patients

Lambert-Eaton News

A new scoring tool can be used to effectively estimate the risk of developing small cell lung cancer (SCLC) for a person with Lambert-Eaton myasthenic syndrome (LEMS), according to a new study. ... Read more

June 18, 2020June 18, 2020

Specific Response Pattern to Nerve Stimulation May Help Diagnose LEMS

Lambert-Eaton News

People with Lambert-Eaton myasthenia syndrome (LEMS) have a specific response pattern to repetitive nerve stimulation — known as RNS — that may enable physicians to easily distinguish such cases from ... Read more

June 11, 2020June 12, 2020

Researchers Studying Cause of Autoimmune Diseases Awarded $1.95M Grant

Lambert-Eaton News

A $1.95 million federal grant has been awarded to researchers investigating the underlying cause of autoimmune diseases, which include Lambert-Eaton myasthenic syndrome (LEMS). Autoimmune disorders, collectively characterized by immune system ... Read more

June 9, 2020July 11, 2020

Coalition Will Address Racial Disparities in Rare Disease Communities

COVID-19 News, Lambert-Eaton News

The Black Women’s Health Imperative (BWHI) recently created a Rare Disease Diversity Coalition focused on reducing racial disparities in the rare disease community. Getting a timely and accurate diagnosis for ... Read more

June 4, 2020June 4, 2020

Autoantibodies Targeting GRP78 Protein May Cause PCD in LEMS

Lambert-Eaton News

Autoantibodies against a protein called GRP78 may lead to paraneoplastic cerebellar degeneration (PCD) in people with Lambert-Eaton myasthenic syndrome (LEMS), a study suggests. The study, “GRP78 antibodies are associated with blood-brain barrier ... Read more

May 29, 2020June 29, 2020

COVID-19 Delaying Rare Disease and Gene Therapy Trials, Pharma Execs Say

COVID-19 News, Lambert-Eaton News

While the ongoing COVID-19 pandemic won’t have much of an impact on cash available for new biotech startups, it has begun to cause delays in the development of gene therapies ... Read more

May 28, 2020May 29, 2020

LEMS-associated Respiratory Problems May Lead to Heart Dysfunction, Case Report Shows

COVID-19 News, Lambert-Eaton News

Lambert‐Eaton myasthenic syndrome-associated diaphragm weakness and subsequent respiratory problems may impair heart function, a case study shows. The report, “Lambert Eaton Myasthenic Syndrome Presenting as Hypoventilation-Induced Right Heart Dysfunction,” was ... Read more

May 25, 2020June 25, 2020

Eurordis Urges Expansion of Newborn Screening Initiatives Across Europe

Lambert-Eaton News

European authorities must step up efforts to screen babies for a multitude of genetic disorders, a panel of experts suggested during a May 14-15 online medical conference. The session was ... Read more

May 21, 2020June 22, 2020

Video Games Connect Chronically Ill Children Isolated at Home, Hospital

COVID-19 News, Lambert-Eaton News

Dara Riva always had a rule that her 10-year-old son could play video games only once a week. But then the COVID-19 pandemic struck, and her perspective changed. Riva’s son, ... Read more

May 20, 2020June 19, 2020

Unity and EU-wide Efforts Focus of Online Rare Disease Meeting

COVID-19 News, Lambert-Eaton News

Eurordis, a Paris-based coalition of national rare disease associations across Europe, hosted its first all-virtual conference, bringing some 1,500 delegates from 57 countries together online during the COVID-19 pandemic. The ... Read more

May 14, 2020May 15, 2020

Catalyst Still Expecting Firdapse Approval in Canada in 2020

COVID-19 News, Lambert-Eaton News

Despite the COVID-19 pandemic, Catalyst Pharmaceuticals is still expecting Firdapse (amifampridine) to be approved for the treatment of Lambert-Eaton myasthenic syndrome (LEMS) in Canada later this year, the company announced in ... Read more

May 7, 2020May 7, 2020

Good Long-term Outcomes Seen in Japanese Study, Regardless of Cancer

Lambert-Eaton News

Japanese patients will Lambert‐Eaton myasthenic syndrome (LEMS) show long-term neurological improvements with treatment regardless of whether they also have small cell lung cancer (SCLC), researchers report. The study, “Long‐term prognosis of Japanese ... Read more

May 4, 2020May 4, 2020

Pregnancy and LEMS

Lambert-Eaton News

Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease characterized by muscle weakness, among other symptoms. It is caused by the production of antibodies that mistakenly attack the point where ... Read more

April 30, 2020April 30, 2020

Lower Electromyography Threshold Improves Accuracy of LEMS Diagnosis, Study Suggests

Lambert-Eaton News

Increments, or increases in nerve responses, greater than 60% in electromyography (EMG) recordings upon short periods of exercise are better at diagnosing Lambert-Eaton myasthenic syndrome (LEMS) than the commonly used ... Read more

April 29, 2020April 29, 2020

Recovery Is a Long Road Following My Concussion

Lambert-Eaton News

When I was diagnosed with Lambert-Eaton myasthenic syndrome (LEMS) in 2016, I quickly learned that I would need to educate everyone else about my ultra-rare disease. The need to educate ... Read more