IBD News Today

September 21, 2020September 22, 2020

ABX464 Effective at Keeping UC Patients in Remission Over Time, Data Show

IBD News Today

ABX464, Abivax’s treatment candidate for ulcerative colitis (UC), continues to be safe and effective over time at keeping patients with moderate-to-severe UC in clinical remission, according to two-year data from a ... Read more

August 31, 2020September 1, 2020

Boosting Tuft Cells Can Reverse Intestinal Inflammation in Mouse Model of Crohn’s

IBD News Today

Specialized cells of the intestine’s outer lining, called tuft cells, reduced chronic intestinal inflammation in a mouse model of Crohn’s disease when activated by the body’s own gut bacteria, according to ... Read more

August 24, 2020August 24, 2020

1st Healthy Volunteer Dosed in Phase 1 Trial of Potential IBD Treatment IMU-856

IBD News Today

The first healthy volunteer has been dosed in an Australian Phase 1 clinical trial investigating IMU-856, a potential novel treatment for inflammatory bowel disease (IBD), according to the therapy’s developer Immunic ... Read more

August 17, 2020August 18, 2020

Budesonide Once-daily Pill Now Available in US for Crohn’s Disease

IBD News Today

Ferring Pharmaceuticals has announced the launch of Ortikos (budesonide), the first and only once-daily pill treatment for people, 8 and older, with mild to moderate Crohn’s disease, in the U.S. ... Read more

August 10, 2020August 11, 2020

Faster DNA Damage in IBD Underlies Higher Risk of Colorectal Cancer, Study Suggests

IBD News Today

A high rate of DNA damage in colon cells underlies the increased risk for colorectal cancer associated with inflammatory bowel disease (IBD), according to a recent study. The study, “Somatic ... Read more

August 3, 2020August 4, 2020

EU Approves More Convenient Formulation of Remsima

COVID-19 News, IBD News Today

The European Commission has approved an under-the-skin injectable formulation of Remsima (infliximab) to treat patients with the two most common forms of inflammatory bowel disease (IBD) — ulcerative colitis and ... Read more

July 27, 2020July 27, 2020

Flavonoids Found in Corn Reduce Bowel Inflammation in IBD Mouse Model

IBD News Today

Scientists have discovered that certain flavonoids — natural compounds in fruits and vegetables that are known for their health benefits — found in corn plants have strong anti-inflammatory properties that ... Read more

July 20, 2020July 20, 2020

Poor Oral Health May Worsen IBD Symptoms

IBD News Today

Inflammatory conditions linked to poor oral health, such as severe gum infections, may worsen inflammatory bowel disease (IBD) by increasing the number of bacteria and immune cells causing gut inflammation, ... Read more

July 13, 2020July 13, 2020

Hulio, Humira Biosimilar, Gets FDA Nod for Crohn’s, UC, But Not Available Until 2023

IBD News Today

The U.S. Food and Drug Administration (FDA) has approved Hulio, a biosimilar of Humira (adalimumab), for the treatment of adults with Crohn’s disease and ulcerative colitis — both forms of inflammatory bowel disease. ... Read more

June 29, 2020June 29, 2020

Celiac Diagnosis Linked to Ten-fold Increased Risk of IBD, Study Finds

IBD News Today

People who have been previously diagnosed with either celiac disease or inflammatory bowel disease (IBD) have an increased risk of being diagnosed with the other illness, according to new research. ... Read more

June 22, 2020June 23, 2020

Stem Cell-related Abnormalities May Predict Recurrence in Crohn’s Disease

IBD News Today

Abnormalities in intestinal stem cell niches may predict recurrence in Crohn’s disease, a new study suggests. These irregularities may result from problems with mitochondria — the so-called powerhouse of cells ... Read more

June 15, 2020June 16, 2020

Scientists Find Variation in JAK2 Gene That Can Lead to IBD

IBD News Today

Scientists have discovered a genetic variation in the janus kinase 2 (JAK2) gene — a gene involved in a signaling pathway implicated in other autoimmune diseases — that can lead ... Read more

June 9, 2020June 10, 2020

Nominations Now Open for Sherman Prizes Honoring Excellence in IBD

IBD News Today

The Bruce and Cynthia Sherman Charitable Foundation is now accepting nominations for the 2020 Sherman Prizes, which recognize individuals working toward improving the lives of people with Crohn’s disease and ... Read more

June 1, 2020June 2, 2020

UK Health Agency Recommends Stelara for Moderately to Severely Active Ulcerative Colitis

IBD News Today

The U.K. National Institute for Health and Care Excellence (NICE) has recommended the use of Stelara (ustekinumab) to treat patients with moderately to severely active ulcerative colitis specifically in adults when ... Read more

May 18, 2020May 18, 2020

Early Phase 2 Trial Data Support Safety, Efficacy of BBT-401 for Ulcerative Colitis

IBD News Today

People with ulcerative colitis may benefit from the experimental oral therapy BBT-401, data from an ongoing Phase 2 clinical trial suggest. These early data also support a good safety profile for ... Read more