Huntington’s Disease News

July 7, 2020July 7, 2020

AFFiRiS’ New Antibody May Help Halt HD Progression, Early Data Suggests

AFFiRiS’ C6-17, a candidate monoclonal antibody for the treatment of Huntington’s disease, is able to target and halt the spread of mutant huntingtin protein — the underlying cause of the neurodegenerative disorder ... Read more

June 30, 2020June 30, 2020

AMT-130, uniQure’s Gene Therapy, Given to First Patient Group in Trial

Huntington's Disease News

A Phase 1/2 clinical trial evaluating AMT-130 as a potential gene therapy for Huntington’s disease has “treated” its first two patients, uniQure announced. One person was given AMT-130 and the other a sham surgery as ... Read more

June 23, 2020June 23, 2020

German Researcher Promotes Non-drug Alternatives for Treating Huntington’s

Huntington's Disease News

At least three major pharmaceutical companies are looking into potential gene therapies for Huntington’s disease — a rare inherited condition without a cure or a treatment to stop its progression. ... Read more

June 15, 2020June 16, 2020

Austedo to Manage Chorea Safe at Higher Doses, Study Finds

Huntington's Disease News

Austedo (deutetrabenazine) can be safely taken at higher than the maximum dose now approved to control involuntary movement in people with Huntington’s disease, an analysis of clinical trial data reported. ... Read more

June 10, 2020July 11, 2020

Coalition Will Address Racial Disparities in Rare Disease Communities

Huntington's Disease News

The Black Women’s Health Imperative (BWHI) recently created a Rare Disease Diversity Coalition focused on reducing racial disparities in the rare disease community. Getting a timely and accurate diagnosis for ... Read more

June 9, 2020June 9, 2020

‘Hero’ Proteins Protect Other Proteins from Stress, Research Finds

Huntington's Disease News

A novel class of proteins, dubbed heat-resistant obscure (Hero) proteins, can protect other proteins from a variety of cellular stresses, and also can prevent the formation of protein aggregates typical ... Read more

June 2, 2020June 2, 2020

Pepinemab Clinical Trial Ongoing; Top-line Results Coming Later this Year

Huntington's Disease News

Vaccinex’s Phase 2 SIGNAL study, evaluating the investigational antibody pepinemab (VX15/2503) in Huntington’s disease patients with late prodromal and early disease, is ongoing and has tested pepinemab in all 265 patients ... Read more

May 28, 2020June 28, 2020

COVID-19 Delaying Rare Disease and Gene Therapy Trials, Pharma Execs Say

COVID-19 News, Huntington's Disease News

While the ongoing COVID-19 pandemic won’t have much of an impact on cash available for new biotech startups, it has begun to cause delays in the development of gene therapies ... Read more

May 26, 2020May 26, 2020

China Approves Austedo for Huntington’s-related Chorea

Huntington's Disease News

Teva Pharmaceuticals’ Austedo (deutetrabenazine tablets) has been approved by China’s National Medical Products Administration (NMPA) for treating chorea associated with Huntington’s disease and tardive dyskinesia in adults. As part of its expedited review process ... Read more

May 25, 2020June 25, 2020

Eurordis Urges Expansion of Newborn Screening Initiatives Across Europe

Huntington's Disease News

European authorities must step up efforts to screen babies for a multitude of genetic disorders, a panel of experts suggested during a May 14-15 online medical conference. The session was ... Read more

May 20, 2020May 20, 2020

Unity and EU-wide Efforts Focus of Online Rare Disease Meeting

Huntington's Disease News

Eurordis, a Paris-based coalition of national rare disease associations across Europe, hosted its first all-virtual conference, bringing some 1,500 delegates from 57 countries together online during the COVID-19 pandemic. The ... Read more

May 19, 2020May 19, 2020

Government Agencies Approve MMJ’s Import of Marijuana for Research

Huntington's Disease News

Multiple government agencies have cooperated to allow MMJ International Holdings to import cannabis extracts to the United States, for use in potential therapies the company is developing for clinical trials ... Read more

May 12, 2020May 12, 2020

Huntington’s Disease Awareness Month Goes Virtual in May Due to Pandemic

Huntington's Disease News

Because of the COVID-19 pandemic, Huntington’s Disease Awareness Month organizers have come up with creative ways to show support and call attention to the disorder during May. In past years, May ... Read more

May 11, 2020June 12, 2020

Rare Diseases Clinical Research Network Opens Online Survey on COVID-19

COVID-19 News, Huntington's Disease News

The Rare Diseases Clinical Research Network (RDCRN) has opened an online survey to better understand how the COVID-19 outbreak is affecting people with rare diseases, their families, and caregivers. Survey ... Read more

May 5, 2020May 5, 2020

Hugging Is One of the Things I Miss the Most

COVID-19 Columns, Huntington's Disease News

The first time I met my wife, Jill, she told me she wasn’t comfortable with “PDA.” Being a smart aleck, I asked her why she didn’t like personal digital assistants. ... Read more