Genetic Obesity News

August 3, 2020August 3, 2020

2 Mutations Linked to High Leptin Levels Found in Adolescent Bulimics

Adolescents with an eating disorder who carry two obesity-related genetic mutations have high levels of the hunger-reducing hormone leptin in their blood, a Mexican study has found. Higher levels of ... Read more

July 23, 2020July 24, 2020

Setmelanotide Prevents Obesity in Mouse Model of POMC Deficiency

COVID-19 News, Genetic Obesity News

Continuous setmelanotide treatment prevented the development of obesity in mice with a form of POMC deficiency in the hypothalamus area of the brain, a study reports. The therapy was also ... Read more

July 20, 2020July 21, 2020

High Fat Diets May Increase Genetic Predisposition to Obesity in Ghana, Study Says

Genetic Obesity News

Adults who carry certain genetic variants that raise their risk of obesity are more susceptible to increases in waist circumference when eating a diet high in total fat and saturated ... Read more

July 16, 2020July 16, 2020

Egyptian Study Links Obesity Risk to Gene Variants Associated With Type 2 Diabetes

Genetic Obesity News

Two gene variants normally associated with type 2 diabetes risk are also linked to obesity in an Egyptian population, a study has found. The study, “Evaluation of genetic susceptibility of ... Read more

July 14, 2020July 14, 2020

National Survey Seeks to Assess Full Social, Economic Burdens of Rare Diseases in US

Genetic Obesity News

The EveryLife Foundation for Rare Diseases has launched a nationwide National Burden of Rare Disease Survey to measure the full implications, economic and social, of living with rare disease in ... Read more

July 13, 2020July 13, 2020

Setmelanotide Reduces Weight, Hunger in Bardet-Biedl Syndrome

Genetic Obesity News

Daily treatment with setmelanotide for one year significantly reduced body weight and hunger in Bardet-Biedl syndrome (BBS) patients with severe obesity, a Phase 2/3 trial shows. The study, “Effect of Setmelanotide, ... Read more

July 9, 2020July 9, 2020

Comprehensive Diagnosis Needed to Pinpoint Pediatric Obesity Causes, Study Suggests

Genetic Obesity News

A broad diagnostic approach that takes into account genetics, hormonal changes, cognitive impairments, and medication use may help identify the underlying cause of pediatric obesity in almost 20% of cases, ... Read more

July 6, 2020July 6, 2020

Obesity Linked to Abnormalities in Brain Structure

Genetic Obesity News

Obesity is associated with brain structural abnormalities in healthy individuals, as well as in those with major depressive disorder (MDD), a study has found. The findings revealed that carrying a ... Read more

July 2, 2020July 6, 2020

Setmelanotide Also Effective in Children with POMC/LEPR Deficiencies, Data Show

Genetic Obesity News

Rhythm Pharmaceuticals’ setmelanotide promotes weight loss not only in adults, but also in children and adolescents with POMC deficiency and LEPR deficiency, two rare genetic obesity disorders, according to updated data from two Phase ... Read more

June 25, 2020June 26, 2020

Setmelanotide Weekly as Safe and Effective as Daily Use, Trial Data Suggest

Genetic Obesity News

A new weekly formulation of setmelanotide, Rhythm Pharmaceuticals’ lead treatment candidate for rare genetic obesity disorders, is as safe and effective in promoting weight loss as the daily formulation, interim data ... Read more

June 23, 2020June 24, 2020

Alexion Charitable Foundation Giving $1.1M to Assist Rare Disease Community During Pandemic

COVID-19 News, Genetic Obesity News

The Alexion Charitable Foundation has awarded $1.1 million in grants to programs that support those with rare diseases during the COVID-19 pandemic, the organization recently announced. The grants will support ... Read more

June 22, 2020June 22, 2020

Vigorous Exercise May Protect Against Effects of Genetic Obesity Risk

Genetic Obesity News

Vigorous physical activity protects against increases in body mass index (BMI) among people, especially white women, at high genetic risk of obesity, according to a new study of adults older ... Read more

June 18, 2020June 18, 2020

MyHeritage Adds Obesity Risk Score to Home Genetic Test

Genetic Obesity News

MyHeritage, a consumer genetic testing company, has added a risk score for genetic obesity and high body mass index (BMI) to its at-home product called MyHeritage DNA Health test. The ... Read more

June 15, 2020June 16, 2020

Exclusive Breastfeeding Eases Weight Gain in Children at High Obesity Risk, Study Finds

Genetic Obesity News

Being fed breast milk exclusively in the first five months of life significantly reduces the genetic risk of becoming obese later in life, and may be a key intervention to ... Read more

June 11, 2020June 12, 2020

POMC Deficiency With High Adiponectin Levels and Obesity Seen in Mouse Study

Genetic Obesity News

In contrast to previous reports, POMC deficiency leads to both obesity and high levels of the protein adiponectin, a study in mice suggested. Shedding light on the molecular workings of ... Read more