Cushing’s Disease News

August 5, 2020August 5, 2020

Isturisa Leads to Rapid, Sustained Reduction in Cortisol Levels, Data Show

Cushing's Disease News

Treatment with Isturisa (osilodrostat) led to a rapid and sustained reduction in cortisol levels and was well-tolerated in people with Cushing’s disease, according to newly published data from the LINC-3 ... Read more

July 29, 2020July 29, 2020

Phase 3 Relacorilant Trial Enrolling Cushing’s Patients With Adrenal Origin

Cushing's Disease News

The first patient has been enrolled in Corcept Therapeutics‘ Phase 3 GRADIENT trial, which is evaluating relacorilant as a potential treatment for people with Cushing’s syndrome due to either an ... Read more

July 24, 2020July 24, 2020

Nizoral May Be Better Choice for Cushing’s Syndrome Patients When Surgery Is Not Available

Cushing's Disease News

In cases where surgery is temporarily unavailable for Cushing’s syndrome patients due to the COVID-19 pandemic, a group of researchers suggest that treatment with Nizoral (ketoconazole) should be considered as ... Read more

July 22, 2020July 22, 2020

Isturisa, Oral Treatment for Cushing’s Syndrome, Available in Germany

Cushing's Disease News

Isturisa (osilodrostat) is now available in Germany to treat adults with endogenous Cushing’s syndrome. The announcement by Recordati Rare Diseases, which acquired rights to Isturisa from its original developer Novartis, follows the ... Read more

July 17, 2020July 17, 2020

Smart Contact Lens Shows Ability to Measure Cortisol Levels

Cushing's Disease News

A newly developed smart contact lens might be used to measure levels of the hormone cortisol in a person’s tears, which could be helpful in disorders such as Cushing’s disease. The ... Read more

July 15, 2020July 15, 2020

Estrogen Receptor Alpha May Be Involved in Development of Cushing’s During Pregnancy

Cushing's Disease News

Estrogen receptor alpha — one of the two main types of protein receptors activated by the female sex hormone estrogen — likely is involved in the development of Cushing’s syndrome ... Read more

July 10, 2020July 10, 2020

Last Patient Completes Withdrawal Phase of Recorlev Trial for Cushing’s

Cushing's Disease News

The last patient has completed the last study visit in the withdrawal phase of the Phase 3 LOGICS clinical trial that is investigating the safety and effectiveness of Recorlev (levoketoconazole) in ... Read more

July 8, 2020July 8, 2020

Adrenal Cushing’s Syndrome More Common in Southeast Asia

Cushing's Disease News

The proportion of Cushing’s syndrome patients whose disease is caused by a tumor in the adrenal glands is higher in Asia than in other continents. Now, researchers in Thailand suggest ... Read more

July 1, 2020July 2, 2020

Isturisa Effective in Treating Cushing’s Syndrome Other Than Cushing’s Disease, Phase 2 Trial Shows

Cushing's Disease News

Recordati’s Isturisa (osilodrostat) safely and effectively normalizes urinary levels of cortisol in people with endogenous Cushing’s syndrome other than Cushing’s disease, according to data from a Phase 2 clinical trial ... Read more

June 24, 2020June 24, 2020

Isturisa Shows Sustained Responses in Cushing’s Disease Patients in LINC-4 Trial

Cushing's Disease News

Isturisa (osilodrostat), an approved therapy for Cushing’s disease, continues to demonstrate high and sustained responses in patients for whom pituitary gland surgery is not an option or whose disease returned after surgery, findings ... Read more

June 23, 2020July 24, 2020

Alexion Charitable Foundation Giving $1.1M to Assist Rare Disease Community During Pandemic

Cushing's Disease News

The Alexion Charitable Foundation has awarded $1.1 million in grants to programs that support those with rare diseases during the COVID-19 pandemic, the organization recently announced. The grants will support ... Read more

June 17, 2020June 17, 2020

Cushing’s Patients Need Special Monitoring in Light of COVID-19, Experts Say

COVID-19 News, Cushing's Disease News

Infection with COVID-19 may appear different and take a distinct clinical course in people with Cushing’s syndrome than in other patients, according to an international team of researchers. Despite an absence ... Read more

June 10, 2020July 11, 2020

Coalition Will Address Racial Disparities in Rare Disease Communities

Cushing's Disease News

The Black Women’s Health Imperative (BWHI) recently created a Rare Disease Diversity Coalition focused on reducing racial disparities in the rare disease community. Getting a timely and accurate diagnosis for ... Read more

June 5, 2020June 7, 2020

Isturisa Now Available in France, Recordati Announces

Cushing's Disease News

Cushing’s syndrome treatment Isturisa (osilodrostat) now is commercially available in France. The announcement from Recordati Rare Diseases comes soon after the medication became fully available for sale and distribution to adults in ... Read more

June 3, 2020June 3, 2020

Isturisa Now Available for Adult Cushing’s Patients in the U.S.

Cushing's Disease News

Isturisa (osilodrostat) oral treatment for Cushing’s disease patients is now fully available to be sold and distributed across the United States, according to its developer Recordati Rare Diseases. The move follows ... Read more