Cushing’s Disease News

October 23, 2020October 23, 2020

UK Organization ’Same But Different’ Announces ‘Glimmer of Hope’ Photo Contest Winner

A photo of a bespectacled young boy, his red baseball cap slightly askew as he enjoys time outside, will be featured on the front cover of an upcoming calendar in ... Read more

October 16, 2020October 16, 2020

Bone Cancer Case Highlights Need for Long-term Monitoring After Radiotherapy for Cushing’s

Cushing's Disease News

A 67-year-old woman developed bone cancer 30 years after receiving radiation therapy to treat Cushing’s disease, according to a case report. Although the risk of bone cancer after radiation therapy ... Read more

October 14, 2020October 14, 2020

Retrospective Cushing’s Diagnosis Done via Hair Test, Case Report Shows

Cushing's Disease News

A woman with undiagnosed Cushing’s disease experienced a resolution of her hypercortisolism symptoms after a spontaneous pituitary apoplexy, and was retrospectively diagnosed via hair cortisol analysis, according to a recent ... Read more

October 9, 2020October 9, 2020

Topical Steroid Use While on HIV Therapy May Lead to Cushing’s, Case Study Shows

Cushing's Disease News

Using steroid-based creams to treat skin conditions in the genital area may lead to the fast development of medication-related Cushing’s syndrome in adults with HIV on antiretroviral therapy with Norvir ... Read more

October 2, 2020October 2, 2020

Obese Patients Don’t Need Cushing’s Screenings Prior to Weight-loss Surgery

Cushing's Disease News

Since morbid obesity by itself is not a telltale sign of Cushing’s syndrome, routine screenings for the disease in obese patients referred for weight-loss surgery is unnecessary, a study reported. ... Read more

September 30, 2020September 30, 2020

Muscle Weakness Persists in Cushing’s Syndrome Despite Remission, Study Finds

Cushing's Disease News

People with Cushing’s syndrome experience muscle weakness that persists even when the disorder is in remission, a new study shows. The study, “Persisting muscle dysfunction in Cushing’s syndrome despite biochemical ... Read more

September 25, 2020September 25, 2020

Patients Prefer ONDST Over 24-Hour Urine Analysis as First Cushing’s Test, Per Study

Cushing's Disease News

Patients prefer the overnight dexamethasone suppression test (ONDST) over the 24-hour urine analysis test as a first screening test for Cushing’s syndrome, a study has found. The study, “Preferred screening ... Read more

September 23, 2020September 23, 2020

Study Provides Further Evidence of Cognitive, Emotional Difficulties in Cushing’s Syndrome

Cushing's Disease News

People with Cushing’s syndrome commonly experience cognitive and emotional problems, a new study indicates. The study, “Neuropsychological and Emotional Functioning in Patients with Cushing’s Syndrome,” was published in Behavioural Neurology. Cushing’s ... Read more

September 18, 2020September 19, 2020

Metopirone Safely Normalized, or Significantly Lowered, Urine Cortisol Levels in Phase 3/4 Trial

Cushing's Disease News

Metopirone (metyrapone) safely normalized, or at least lowered by half, the levels of cortisol found in the urine of patients with endogenous Cushing’s syndrome, according to data from a Phase ... Read more

September 16, 2020September 16, 2020

2 Cancer Meds May be Promising Combo Treatment for Cushing’s Disease

Cushing's Disease News

A combination of bexarotene and lapatinib, two approved anti-cancer medications, may hold promise in treating Cushing’s disease, according to a recent study. The study, “Bexarotene combined with lapatinib for the treatment of ... Read more

September 11, 2020September 11, 2020

LOGICS Trial Supports Recorlev’s Efficacy in Lowering Cortisol Levels

Cushing's Disease News

Patients with endogenous Cushing’s syndrome who stopped using Recorlev (levoketoconazole) and moved to a placebo in a study started having their urine cortisol levels rise in response to lack of treatment, ... Read more

September 9, 2020September 9, 2020

High Cortisol Levels in Urine May Be Linked to Changes in Blood Sugar Metabolism

Cushing's Disease News

Abnormally high levels of cortisol in the urine — one of the hallmarks of Cushing’s syndrome — seem to be associated with alterations in blood sugar metabolism in obese patients, ... Read more

September 4, 2020September 5, 2020

New Cushing’s Saliva Test Does Not Meet Standard Methods

Cushing's Disease News

An alternative diagnostic test to measure the levels of late-night cortisol in the saliva of patients with Cushing’s disease did not meet the standards of currently used methods, a study ... Read more

August 26, 2020September 28, 2020

Xperiome Platform Aims to Streamline Searches for Rare Diseases, Gain Patient Input

Cushing's Disease News

Raremark, an online rare disease patient community, has launched a digital platform called Xperiome, aimed at streamlining the search for new medicines for rare disorders and incorporating more patient input ... Read more

August 21, 2020August 21, 2020

Dissolving Hydrocortisone Tablets for CAH May Lead to Higher Dosing, Cushing’s

Cushing's Disease News

Dissolving hydrocortisone tablets in water for multiple daily dosing to treat congenital adrenal hyperplasia (CAH) in children may result in higher-than-intended dosing and exogenous Cushing’s syndrome — a form of ... Read more