Cold Agglutinin News

November 20, 2020November 20, 2020

Manufacturing Deficiencies Delay FDA Decision on Sutimlimab for Adults

The U.S. Food and Drug Administration (FDA) has issued a complete response to Sanofi’s application requesting that its investigational therapy sutimlimab be approved for treating hemolysis — the breakdown of ... Read more

November 13, 2020November 13, 2020

Poor Prognosis for Lymphoma-associated AIHA, Case Report Shows

Cold Agglutinin News

People with non-Hodgkin’s lymphoma (NHL) — a type of blood cancer — that co-occurs with autoimmune hemolytic anemia (AIHA) have a poor prognosis, suggesting a need for further research into ... Read more

November 6, 2020November 6, 2020

Apellis, Sobi Partner on Systemic Pegcetacoplan for CAD, Other Rare Diseases

Cold Agglutinin News

Apellis Pharmaceuticals and Swedish Orphan Biovitrum (Sobi) are collaborating to advance the development of systemic pegcetacoplan, or APL-2, in the treatment of cold agglutinin disease (CAD) and other disorders, the ... Read more

October 30, 2020October 30, 2020

UK Organization ’Same But Different’ Announces ‘Glimmer of Hope’ Photo Contest Winner

Cold Agglutinin News

A photo of a bespectacled young boy, his red baseball cap slightly askew as he enjoys time outside, will be featured on the front cover of an upcoming calendar in ... Read more

October 23, 2020October 23, 2020

CAD, Other Hemolytic Anemias Increased in Denmark for Past 4 Decades, Study Finds

Cold Agglutinin News

The incidence and prevalence of most acquired hemolytic disorders, including cold agglutinin disease (CAD), have been rising in Denmark in the past decades, regardless of age and sex, a retrospective study ... Read more

October 21, 2020November 22, 2020

Telehealth ‘Helpful’ Alternative to In-person Care, Rare Disease Patients Say

Cold Agglutinin News, COVID-19 News

A majority of rare disease patients using telehealth during the COVID-19 pandemic thought the experience positive, and many would like the option of continuing its use in future appointments, a series ... Read more

October 16, 2020October 16, 2020

Infant CAD May Be Treated With IV Immunoglobulin, Case Report Suggests

Cold Agglutinin News

The case of an infant who developed cold agglutinin disease (CAD) shortly after being vaccinated suggests that intravenous immunoglobulin may be an effective treatment for young children with the autoimmune ... Read more

October 9, 2020October 10, 2020

Secondary CAD May Cause Complications in Cases of Severe COVID-19

Cold Agglutinin News, COVID-19 News

Cold agglutinin disease (CAD) may develop as a result of severe COVID-19, further complicating laboratory tests and treatment for these individuals, according to a case report in two patients. The ... Read more

October 7, 2020November 8, 2020

Same But Different Asks Public to Vote on ‘Glimmer of Hope’ Calendar Photos

Cold Agglutinin News, COVID-19 News

Same But Different, a nonprofit U.K. group that uses art for social change, is inviting people to choose their favorite photographs in a calendar contest to heighten awareness of rare diseases, ... Read more

October 2, 2020October 2, 2020

Cancer Treatment With Keytruda May Lead to CAD, Case Report Suggests

Cold Agglutinin News

Treatment with the cancer immunotherapy Keytruda (pembrolizumab) can lead to the development of cold agglutinin disease (CAD), the case of a lung cancer patient demonstrates. The report, “Pembrolizumab-Induced Cold Agglutinin Disease,” ... Read more

September 25, 2020September 25, 2020

CAD Least Common Autoimmune Hemolytic Anemia in India, Study Suggests

Cold Agglutinin News

Cold agglutinin disease (CAD) seems to be the least common form of autoimmune hemolytic anemia (AIHA) in India, affecting about 15% of patients with the rare disorder, a study has ... Read more

September 18, 2020September 18, 2020

Fall Uncovers Undiagnosed CAD in Elderly Woman, Case Study Reports

Cold Agglutinin News

Researchers in the U.K. have described the case of an 81-year-old woman who was diagnosed with secondary cold agglutinin disease (CAD) only after falling and being treated at the hospital ... Read more

September 9, 2020September 9, 2020

CAD Possible in COVID-19 Patients With Blood Clotting Problems, Case Report Finds

Cold Agglutinin News, COVID-19 News

Physicians should consider testing patients with COVID-19 and thrombosis for different forms of autoimmune hemolytic anemia (AIHA), including cold agglutinin disease (CAD), which may underlie their blood clotting issues, a ... Read more

September 2, 2020September 3, 2020

CAD in COVID-19 Patients Warrants M. Pneumoniae Test

Cold Agglutinin News, COVID-19 News

The presence of cold agglutinin disease (CAD) without red blood cells’ destruction in patients with COVID-19 should prompt clinicians to test for Mycoplasma pneumoniae, as this type of bacteria also ... Read more

August 26, 2020August 26, 2020

Study Supports Use of Rituximab-containing Therapies in CAD

Cold Agglutinin News

Therapies that contain Rituximab may be effective for people with cold agglutinin disease (CAD), a study suggests. The study, “Rituximab-containing therapy for cold agglutinin disease: a retrospective study of 16 ... Read more