Charcot-Marie-Tooth News

October 23, 2020October 23, 2020

CMT UK Offering Video Series of Exercises for Home Use

To promote physical activity in people with Charcot-Marie-Tooth (CMT) disease, the charity CMT UK shared seven exercise videos that patients can carry out in the comfort of their home. The exercises ... Read more

October 16, 2020October 16, 2020

Functional Loss in CMT1A Patients May Cause Brain to Reorganize, Study Indicates

Charcot-Marie-Tooth News

Patients with Charcot Marie Tooth Type 1A (CMT1A) disease appear to experience a structural reorganization in their brains, particularly in a region associated with movement and balance called the cerebellum, ... Read more

October 13, 2020October 13, 2020

Curcumin Particles Show Potential to Ease Symptoms in CMT1A Rat Model

Charcot-Marie-Tooth News

A new formulation of an antioxidant called curcumin may be effective in alleviating the symptoms of Charcot-Marie-Tooth type 1A (CMT1A) disease, a rat study suggests. The formulation was seen to ... Read more

October 9, 2020October 9, 2020

Bioinformatics Study Identifies 30 New Genes Potentially Involved in CMT

Charcot-Marie-Tooth News

Using bioinformatics — computer-based analyses of biological data — scientists discovered 30 new genes that might be involved in Charcot-Marie-Tooth disease (CMT). Their findings also provide new insights into the ... Read more

October 6, 2020October 7, 2020

Scientists Discover Potential Therapeutic Target for CMT in Mouse Study

Charcot-Marie-Tooth News

Blocking a protein called CMTM6 in myelin-producing cells increases the thickness of nerve fibers and the speed at which electrical signals travel along their length, a mouse study has found. ... Read more

October 2, 2020October 2, 2020

CMT&Me Launches Global Fundraising Contest for CMT Awareness Month in Europe

Charcot-Marie-Tooth News

This October, in observance of Charcot-Marie-Tooth disease (CMT) awareness month in Europe, the CMT&Me study is launching an international competition aimed at informing people about this group of inherited disorders, ... Read more

September 29, 2020September 29, 2020

DTx Pharma Receives NIH Funding to Advance RNA-based Therapies for CMT

Charcot-Marie-Tooth News

The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), has awarded DTx Pharma a funding grant to advance development of promising new therapeutic candidates ... Read more

September 25, 2020September 25, 2020

3 New GJB1 Mutations Found in Chinese Patients That Could Cause CMTX1

Charcot-Marie-Tooth News

Three new genetic mutations in the GJB1 gene have been found inn Chinese patients that can cause X-linked Charcot-Marie-Tooth (CMTX1) disease, expanding the diversity of mutations causing the condition, according ... Read more

September 22, 2020September 22, 2020

New HDAC6 Inhibitor Shows Myelination Potential in CMT1A Models

Charcot-Marie-Tooth News

CKD-504, a new compound that works to block the protein HDAC6, was found to restore myelination in cell and mouse models of Charcot-Marie-Tooth disease type 1A (CMT1A) in an early study. ... Read more

September 18, 2020September 18, 2020

DST Gene Mutations Also Can Cause CMT Type 2, Study Finds

Charcot-Marie-Tooth News

Mutations in the DST gene that affect the normal functioning of nerve fibers can cause Charcot-Marie-Tooth disease (CMT) type 2, a new study shows. This gene has not previously been ... Read more

September 15, 2020September 15, 2020

CMT1A Patients Needed for Study Seeking New Ways to Monitor Disease Progression

Charcot-Marie-Tooth News

A new study is recruiting adults with Charcot-Marie-Tooth disease (CMT) type 1A to find better methods for measuring disease progression in this patient population, the Hereditary Neuropathy Foundation announced in a press ... Read more

September 11, 2020September 11, 2020

Pharnext, CMT Association Partner on CMT1A Biomarkers to Support Phase 3 Study

Charcot-Marie-Tooth News

Pharnext and the Charcot-Marie-Tooth Association (CMTA) have partnered to find new biomarkers associated with Charcot-Marie-Tooth disease type 1A (CMT1A), the most common subtype of the disease, according to a press ... Read more

September 8, 2020September 8, 2020

CMTA Turned Annual Camp Footprint Into ‘Empowered’ 5-Day Virtual Event

Charcot-Marie-Tooth News, COVID-19 News

This summer, the Charcot-Marie-Tooth Association (CMTA) turned its annual Camp Footprint for children and teens with CMT disease into a virtual experience. The unique initiative, which was launched by the ... Read more

September 4, 2020September 4, 2020

CMT Research Foundation Calls for Action During Awareness Month

Charcot-Marie-Tooth News

The CMT Research Foundation (CMTRF) wants to turn September from Awareness Month into “CMT Action Month.” This year, the foundation is seeking to turn awareness of Charcot-Marie-Tooth (CMT) disease into action ... Read more

September 1, 2020September 1, 2020

Virtual Activities Abound for CMT Awareness Month in September

Charcot-Marie-Tooth News

From participating in a virtual dog walk, to switching out Facebook photo frames, advocates are set to mark Charcot-Marie-Tooth (CMT) Awareness Month, observed every September. Awareness and education are crucial to ... Read more