Bronchiectasis News Today

January 11, 2021January 11, 2021

Measuring Procalcitonin in Sputum May Help Manage Flare-ups

Levels of procalcitonin, the precursor of the hormone calcitonin, are higher in samples of coughed-up mucus from people with bronchiectasis during episodes of acute flare-ups. These findings suggest procalcitonin as ... Read more

January 8, 2021January 8, 2021

RHB-204, Oral Treatment for MAC Lung Infections, Put on FDA Fast Track

Bronchiectasis News Today

The U.S. Food and Drug Administration (FDA) has given fast track designation to RedHill Biopharma’s RHB-204 as a potential first-line and stand-alone, oral treatment for lung infections caused by Mycobacterium ... Read more

January 4, 2021January 4, 2021

Corticosteroid Use Higher in Children With Bronchiectasis Who Have Asthma

Bronchiectasis News Today

Children with non-cystic fibrosis (CF) bronchiectasis are more likely be prescribed inhaled corticosteroids — medications normally used to treat asthma — to manage their disease when they have certain asthma-like ... Read more

December 21, 2020December 21, 2020

Hypertonic Saline May Boost Benefits of Airway Clearance Techniques in Children

Bronchiectasis News Today

Airway clearance techniques (ACTs) incorporating the use of hypertonic saline solutions — solutions with a higher salt concentration than blood plasma — for nebulization can improve lung function and lower ... Read more

December 18, 2020December 18, 2020

Endothelial Progenitor Cells (EPCs) Linked to Disease Severity in Study

Bronchiectasis News Today

People with bronchiectasis have lower-than-normal numbers of endothelial progenitor cells (EPCs) in their blood, a study suggests. The results indicate a link between low EPC activity and greater disease severity. ... Read more

December 14, 2020December 14, 2020

Young Bronchiectasis Patients Less Prepared to Shift to Adult Healthcare, NZ Study Finds

Bronchiectasis News Today

Young patients with non-CF bronchiectasis are less prepared than those with cystic fibrosis (CF) to transition from pediatric to adult healthcare services, a study in New Zealand has found. This ... Read more

December 11, 2020December 11, 2020

Savara Discontinues Apulmiq Program for NCFB Amid Cost-cutting Measures

Bronchiectasis News Today

Savara Pharmaceuticals has discontinued its clinical program of the inhaled antibiotic formulation Apulmiq (ciprofloxacin) for the treatment of non-cystic fibrosis bronchiectasis (NCFB). This decision comes with the announcement of Savara‘s ... Read more

December 7, 2020December 7, 2020

Study Recommends Longer Rest Interval Between 6-min Walk Tests for Non-CF Bronchiectasis Patients

Bronchiectasis News Today

Two consecutive six-minute walk tests (6MWT) — which measure the distance a patient can walk in that time to assess their exercise capacity — with the recommended rest interval of ... Read more

December 4, 2020December 4, 2020

Phase 3 ASPEN Trial Testing Brensocatib Now Recruiting; First Patient Dosed

Bronchiectasis News Today

The first participant has been dosed in ASPEN, a Phase 3 trial — now recruiting patients — that is evaluating the investigational medication brensocatib in people with non-cystic fibrosis (CF) ... Read more

December 3, 2020January 4, 2021

NORD Push for Rare Disease Advisory Councils Focus of Dec. 16 Public Meeting

Bronchiectasis News Today

To empower and equip members of the rare disease community to engage state leaders in matters of importance to patients and their families, the National Organization for Rare Disorders (NORD) ... Read more

November 26, 2020December 28, 2020

Survey Finds COVID-19 Disrupted Care, Well-Being of Rare Disease Patients in Europe

Bronchiectasis News Today, COVID-19 News

The first wave of COVID-19 in Europe severely disrupted access to care and raised stress and anxiety in people with rare diseases, negatively affecting their health and well-being, according to a ... Read more

November 23, 2020November 23, 2020

RedHill Launches Trial to Test RHB-204 for Bronchiectasis Plus MAC Lung Infections

Bronchiectasis News Today

RedHill Biopharma has launched a Phase 3 clinical trial to evaluate the safety and effectiveness of its investigational oral therapy RHB-204 in adults with bronchiectasis who have lung infections caused ... Read more

November 20, 2020December 24, 2020

Latest NORD Webinar Offers Insights on Starting Nonprofit, Patient Registry

Bronchiectasis News Today

Leaders in the U.S. rare disease community came together recently for a webinar to present helpful information on how to start a nonprofit and patient registry. They shared about how ... Read more

November 16, 2020November 16, 2020

EMA Grants PRIME Status to Brensocatib for Treating Non-CF Bronchiectasis

Bronchiectasis News Today

The European Medicines Agency (EMA) has given the designation of priority medicines, or PRIME, to Insmed’s brensocatib for the treatment of non-cystic fibrosis bronchiectasis (NCFBE). A PRIME designation is given ... Read more

November 13, 2020November 13, 2020

Bronchiectasis Worsens Lung Function, Quality of Life in Severe Asthma, Study Finds

Bronchiectasis News Today

People with severe asthma have worse lung function, lower quality of life, and more exacerbations if they also have bronchiectasis, an Italian study found. The study, “Clinical features associated with ... Read more