Angioedema News

July 24, 2020July 25, 2020

More Research Needed on Pregnancy-related HAE Attacks, Case Report Shows

Angioedema News

More insight and study is needed into the symptoms, proper management, and potential complications of pregnancy-related hereditary angioedema (HAE) attacks, according to a case report of a woman who is ... Read more

July 22, 2020July 23, 2020

KalVista Anticipates Milestones in 2 HAE Treatment Candidates in Second Half of 2020

Angioedema News

KalVista Pharmaceuticals anticipates beginning a Phase 2 clinical trial in the second half of this year to test KVD824, an investigational preventive treatment for hereditary angioedema (HAE). In addition, the ... Read more

July 17, 2020July 17, 2020

HAE International Translates Printable Emergency Card into 34 Languages

Angioedema News

HAE International, a global nonprofit that supports local hereditary angioedema (HAE) patient groups and organizations, has expanded their emergency card template to a total of 34 languages — and plans ... Read more

July 15, 2020July 15, 2020

Cipla Given FDA Approval for Icatibant, Generic Version of Firazyr

Angioedema News

Cipla has received final approval from the U.S. Food and Drug Administration (FDA) for a generic version of Firazyr (icatibant injection), an approved treatment for acute attacks in adults with hereditary angioedema ... Read more

July 1, 2020July 2, 2020

Preventive Takhzyro Reduces HAE Attacks Early in Treatment, Analysis Shows

Angioedema News

Preventive treatment with Takhzyro (lanadelumab) significantly reduces the number of swelling attacks in people with hereditary angioedema (HAE), even in the early phases of treatment, a post hoc analysis from the HELP ... Read more

June 26, 2020June 29, 2020

Haegarda Safe, Effective in Older HAE Patients, Trial Analysis Shows 

Angioedema News

Regular Haegarda treatment in older people with hereditary angioedema (HAE) — those ages 65 and older — was well-tolerated and effective in stopping HAE-related attacks, a post-hoc analysis of the COMPACT ... Read more

June 24, 2020June 24, 2020

Prophylactic Takhzyro Effective for Broad Range of HAE Patients, Study Suggests

Angioedema News

Preventive treatment with Takhzyro (lanadelumab) is effective at delaying and lowering the monthly rate of attacks in a broad range of patients with hereditary angioedema (HAE), a study has found. ... Read more

June 22, 2020July 24, 2020

Alexion Charitable Foundation Giving $1.1M to Assist Rare Disease Community During Pandemic

Angioedema News, COVID-19 News

The Alexion Charitable Foundation has awarded $1.1 million in grants to programs that support those with rare diseases during the COVID-19 pandemic, the organization recently announced. The grants will support ... Read more

June 19, 2020June 19, 2020

Ruconest More Cost-effective Than Other On-demand Treatments for HAE Attacks

Angioedema News

Ruconest, a recombinant human form of the C1 inhibitor protein, is more cost-effective than other on-demand therapies at treating attacks in people with hereditary angioedema, a new study suggests. The ... Read more

June 17, 2020June 17, 2020

Garadacimab Reduces HAE Attacks Significantly, Preliminary Phase 2 Trial Results Show

Angioedema News

Preliminary results from a Phase 2 clinical trial testing the investigational therapy garadacimab for the treatment of hereditary angioedema (HAE) show a more than 88% reduction in the number of attacks, ... Read more

June 12, 2020June 13, 2020

Data Support Long-term Efficacy of Berotralstat in HAE

Angioedema News

New clinical trial data show that BioCryst Pharmaceuticals‘ investigational therapy for hereditary angioedema (HAE), berotralstat, reduces the frequency of HAE attacks and improves patients’ quality of life through 48 weeks ... Read more

June 10, 2020July 11, 2020

Coalition Will Address Racial Disparities in Rare Disease Communities

Angioedema News, COVID-19 News

The Black Women’s Health Imperative (BWHI) recently created a Rare Disease Diversity Coalition focused on reducing racial disparities in the rare disease community. Getting a timely and accurate diagnosis for ... Read more

June 5, 2020June 5, 2020

Patent Allowance Extends BioCryst’s Protection of Berotralstat for HAE

Angioedema News

The U.S. Patent and Trademark Office (USPTO) issued a new allowance for a patent submitted by BioCryst Pharmaceuticals for berotralstat (BCX7353), an investigational therapy to treat hereditary angioedema (HAE). The ... Read more

June 3, 2020June 4, 2020

Prefilled Syringe for At-home Use of Takhzyro Favored for Approval in EU

Angioedema News

The Committee for Medicinal Products for Human Use (CHMP), part of the European Medicines Agency (EMA), is recommending the approval of a prefilled syringe to administer Takhzyro (lanadelumab), a preventative treatment ... Read more

May 29, 2020June 29, 2020

COVID-19 Delaying Rare Disease and Gene Therapy Trials, Pharma Execs Say

Angioedema News, COVID-19 News

While the ongoing COVID-19 pandemic won’t have much of an impact on cash available for new biotech startups, it has begun to cause delays in the development of gene therapies ... Read more