ANCA Vasculitis News

September 23, 2020September 23, 2020

Exagen Launches Test for Rapid Diagnosis, Differentiation of AAV Subtypes

Exagen, a life sciences company developing tests for the diagnosis, prognosis, and monitoring of autoimmune conditions, has launched a new test for the rapid diagnosis of ANCA-associated vasculitis (AAV). Named ... Read more

September 21, 2020September 21, 2020

FDA to Consider Avacopan as Potential Oral Treatment of AAV

ANCA Vasculitis News

The U.S. Food and Drug Administration (FDA) has accepted for review ChemoCentryx‘s application requesting the approval of avacopan to treat ANCA-associated vasculitis (AAV), the company announced in a press release. The agency ... Read more

September 16, 2020September 16, 2020

20S-proteasome May Be Useful Biomarker of AAV Disease Activity

ANCA Vasculitis News

The 20S-proteasome — the core of an enzyme complex responsible for eliminating unnecessary or damaged proteins in cells — may be a useful biomarker of disease activity in people with ... Read more

September 10, 2020September 10, 2020

AAV Carries High Healthcare Costs, Italian Study Finds

ANCA Vasculitis News

ANCA-associated vasculitis (AAV) carries high healthcare costs for therapies and hospitalizations to treat the disease itself and related infections, a study in Italy has found. The study, “Healthcare and economic ... Read more

September 3, 2020September 3, 2020

Muscle Biopsies Could Be Useful in AAV Diagnosis, Study Asserts

ANCA Vasculitis News

Muscle biopsies could be used to diagnose ANCA-associated vasculitis (AAV), a new study indicates. The finding suggests that such biopsies are most informative in females or in people with certain ... Read more

August 31, 2020August 31, 2020

Organ Involvement in EGPA Patients Impacted by ANCA Status, Review Finds

ANCA Vasculitis News

The presence or absence of ANCA antibodies appears to influence which organs are affected by eosinophilic granulomatosis with polyangiitis (EGPA), a rarer subtype of ANCA-associated vasculitis, a recent review of ... Read more

August 27, 2020August 28, 2020

Xperiome Platform Aims to Streamline Searches for Rare Diseases, Gain Patient Input

ANCA Vasculitis News

Raremark, an online rare disease patient community, has launched a digital platform called Xperiome, aimed at streamlining the search for new medicines for rare disorders and incorporating more patient input ... Read more

August 17, 2020August 17, 2020

EveryLife Foundation Launches Scholarship Fund for Rare Disease Community in US

ANCA Vasculitis News

The EveryLife Foundation for Rare Diseases has launched a scholarship fund in the U.S. to support individuals with rare disorders who are pursuing personal goals through training and education. The ... Read more

August 17, 2020August 17, 2020

Extracellular Vesicles of Neutrophils May Be Blood Biomarkers for AAV

ANCA Vasculitis News

Extracellular vesicles, or the tiny membrane-bound particles that are released from cells, could be used as a blood biomarker of disease activity in people with ANCA-associated vasculitis (AAV), a new study ... Read more

August 13, 2020August 14, 2020

Complement System Overactive in AAV Patients With Active Disease

ANCA Vasculitis News

The complement system, a part of the immune system, is overactive in people with active ANCA-associated vasculitis (AAV), but achieving remission appears to lower most of its components to normal ... Read more

August 11, 2020September 11, 2020

New Streaming Channel Showcases Rare Disease Films

ANCA Vasculitis News, COVID-19 News

When the COVID-19 pandemic forced the postponement of a rare disease film festival originally slated for May, its organizers set out to find a new way to bring the films ... Read more

August 6, 2020August 6, 2020

Plasma Exchange Does Not Improve Survival of Severe AAV Patients, Study Suggests

ANCA Vasculitis News

Plasma exchange does not prolong the survival of patients with severe ANCA-associated vasculitis connected with diffuse alveolar hemorrhage, a potentially life-threatening condition in which blood starts to build up in the ... Read more

July 30, 2020July 30, 2020

ANCA Status, B-cell Levels After Rituximab Treatment Predict Relapses

ANCA Vasculitis News

The presence of detectable ANCA antibodies and B-cells after initial treatment with rituximab — used to induce remission in people with ANCA-associated vasculitis (AAV) — predicts a greater risk of ... Read more

July 27, 2020July 27, 2020

Complement System Activation May Be Linked to Kidney Disease in AAV Patients

ANCA Vasculitis News

The complement system, a component of the immune system, is overactive in people with necrotizing glomerulonephritis, or inflammation in the tiny blood vessels of the kidneys, caused by ANCA-associated vasculitis ... Read more

July 23, 2020July 23, 2020

Fingolimod May Have Potential as AAV Treatment, Rat Study Indicates

ANCA Vasculitis News

Fingolimod (FTY720), a medication used to treat multiple sclerosis, also appears to ease many of the symptoms of ANCA-associated vasculitis (AAV), a new study in rats suggests. The study, “Sphingosine-1-phosphate ... Read more