ANCA Vasculitis News

January 17, 2022January 17, 2022

Immunosuppressant MMF More Effective in Cases With Kidney Issues

Mycophenolate mofetil (MMF), an immunosuppressant, may sustain remission more efficiently than other therapies in ANCA-associated vasculitis (AAV) patients who have kidney symptoms, a review of clinical trials found. The findings ... Read more

January 12, 2022January 13, 2022

COVID-19 Exposure Could Trigger AAV, Case Report Suggests

ANCA Vasculitis News, COVID-19 News

ANCA-associated vasculitis (AAV) may be a rare complication of exposure to COVID-19 proteins, either through infection or vaccination, a report covering two women suggests. Both were diagnosed early and improved ... Read more

January 10, 2022January 10, 2022

PR3-ANCA Antibodies Tied to More Relapses in EGPA Patients

ANCA Vasculitis News

People with eosinophilic granulomatosis with polyangiitis (EGPA) who carry antibodies against the proteinase 3 (PR3) protein have more frequent relapses and a shorter time to relapse or death than patients ... Read more

January 5, 2022January 5, 2022

Moderna COVID-19 Vaccine May Trigger AAV-linked Kidney Damage

ANCA Vasculitis News, COVID-19 News

Kidney inflammation associated with ANCA-associated vasculitis (AAV) was recently reported in a man following his second dose of the Moderna COVID-19 vaccine. While cases of AAV have been described after ... Read more

January 3, 2022January 4, 2022

Study Identifies Early Risk Factors for Kidney Failure in AAV

ANCA Vasculitis News

Poor kidney function and worse overall disease severity at diagnosis can predict kidney failure in adults with ANCA-associated vasculitis (AAV), according to a small single-center study in Turkey. In addition, ... Read more

December 29, 2021December 30, 2021

Rituximab for AAV Linked to Poor Responses to COVID-19 Vaccines

ANCA Vasculitis News, COVID-19 News

Treatment with the CD20 inhibitor rituximab is significantly associated with poor antibody responses to COVID-19 vaccines among people with ANCA-associated vasculitis (AAV), a study found. However, the number of antibody-producing ... Read more

December 22, 2021December 23, 2021

Vasculitis Foundation Needs Help Reaching Goals in 2022

ANCA Vasculitis News

Winding up its 35th year, the U.S.-based Vasculitis Foundation (VF) is making its annual call for support for its programs and initiatives, which aim to help existing and future vasculitis ... Read more

December 20, 2021December 21, 2021

Immunoadsorption May Help Push AAV Into Remission More Quickly

ANCA Vasculitis News

Immunoadsorption, a procedure that removes specific antibodies from the blood, may speed remission in patients with ANCA-associated vasculitis (AAV) and serious kidney disease and help more patients attain this outcome, ... Read more

December 15, 2021December 16, 2021

Blood Levels of Proteins Identify Active AAV in Long-term Study

ANCA Vasculitis News

Blood levels of several proteins — CXCL13, interleukins IL-6, IL-8, IL-15, IL-18 binding protein (IL-18BP), matrix metalloproteinase-3 (MMP-3), and erythrocyte sedimentation rate (ESR) — were validated as effective at identifying ... Read more

December 13, 2021December 14, 2021

Kidney Transplant Generally Safe in Children With AAV, Study Suggests

ANCA Vasculitis News

Outcomes of kidney transplants for children with kidney failure related to ANCA-associated vasculitis (AAV) are comparable to outcomes of transplants for children with other causes of kidney disease, highlighting that ... Read more

December 8, 2021December 9, 2021

Cardiovascular Disease Risk Likely Increases After AAV Diagnosis

ANCA Vasculitis News

People with ANCA-associated vasculitis (AAV) have a higher risk of cardiovascular disease, especially in the months immediately following AAV diagnosis, a population-based analysis found. “Our study demonstrates a key ‘high-risk ... Read more

December 6, 2021December 6, 2021

Older Patients Have Worse Mortality, but Treatment Helps All Ages

ANCA Vasculitis News

People over the age of 65 with ANCA-associated vasculitis (AAV) have worse mortality outcomes than younger patients, but kidney failure is not greater in this group, according to a recent ... Read more

December 1, 2021December 2, 2021

AAV Patients Independently Adopt Self-management Techniques

ANCA Vasculitis News, COVID-19 News

People with ANCA-associated vasculitis (AAV) adopt a range of strategies that help them to better cope with the condition on their own, but several areas of self-management could be addressed ... Read more

November 29, 2021November 30, 2021

Study Reveals Difficulties in Diagnosing GPA for Patients in Saudi Arabia

ANCA Vasculitis News

The case of a man in Saudi Arabia with granulomatosis with polyangiitis (GPA), a form of ANCA-associated vasculitis, highlights the difficulties that can occur in diagnosing this disease, a case ... Read more

November 24, 2021November 25, 2021

Progranulin Protein Levels in Blood May Predict AAV Severity

ANCA Vasculitis News

Blood levels of progranulin — a protein involved in cell development, cell growth, and wound healing — may predict the severity of ANCA-associated vasculitis (AAV), a new observational study suggests. ... Read more