ANCA Vasculitis News

June 15, 2022June 15, 2022

AAV Emerges in Boy Using Levamisole to Treat Kidney Disease

ANCA-associated vasculitis (AAV) emerged as a side effect of levamisole given for years to treat a 15-year-old boy with idiopathic nephrotic syndrome, according to a case report. “By reporting this ... Read more

June 13, 2022June 13, 2022

Man Develops AAV Following Blood Stem Cell Transplant: Case Study

ANCA Vasculitis News

A 65-year-old man developed granulomatosis with polyangiitis (GPA), a type of anti-neutrophilic cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), after receiving a stem cell transplant for another autoimmune condition, according to a ... Read more

June 8, 2022June 8, 2022

EGPA Patient and Doctor Differences in Disease Reporting Noted

ANCA Vasculitis News

People with eosinophilic granulomatosis with polyangiitis (EGPA) are more likely to report a greater range of symptoms than their doctors, a study that drew on patient- and physician-reported databases found, ... Read more

June 6, 2022June 6, 2022

Case of GPA With High Urine Protein Is Unusual

ANCA Vasculitis News

A man with granulomatosis with polyangiitis — a type of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) — and abnormally raised urine protein levels, a sign of kidney disease, has been ... Read more

June 1, 2022June 1, 2022

Subtype of B-cells Linked to Kidney Disease in AAV, Study Discovers

ANCA Vasculitis News

A subtype of antibody-producing B-cells was significantly higher in the bloodstream of ANCA-associated vasculitis (AAV) patients with active kidney involvement compared with those who were in remission and healthy individuals. ... Read more

May 25, 2022May 25, 2022

AAV Patients With Skin Lesions May Be ANCA-Negative, Study Finds

ANCA Vasculitis News

Many ANCA-associated vasculitis (AAV) patients with skin lesions test negative for ANCA antibodies — proteins produced by the immune system that bind to white blood cells called neutrophils, ultimately triggering ... Read more

May 23, 2022May 23, 2022

Lung, ENT Involvement, Steroid Use Reduced With Tavneos: ADVOCATE

ANCA Vasculitis News

Tavneos (avacopan) reduced respiratory, ear, nose, and throat (ENT) involvement among people with ANCA-associated vasculitis (AAV), but did not significantly outperform prednisone in its ability to do so, according to ... Read more

May 18, 2022May 18, 2022

Relapses Less Likely in Patients With Past Autoimmune Disorder: Study

ANCA Vasculitis News

People with a past history of autoimmune disease before developing ANCA-associated vasculitis (AAV) have significantly fewer relapses after achieving remission, a study reported. Post-remission chances of a relapse were 67% lower ... Read more

May 16, 2022May 16, 2022

Rituximab Remission Rates Similar in Mexicans as in Other Populations

ANCA Vasculitis News, COVID-19 News

Rituximab treatment led to rates of remission and relapse prevention in Mexican patients with ANCA-associated vasculitis (AAV) that were similar to those previously observed in other patient populations, a real-world ... Read more

May 11, 2022May 11, 2022

Kidney Impairment Likely Where Rheumatoid Arthritis, AAV Coexist

ANCA Vasculitis News

People with rheumatoid arthritis (RA) who also have ANCA-associated vasculitis (AAV) are more likely to develop signs of kidney impairment than those without AAV, a small study showed. Among patients ... Read more

May 9, 2022May 9, 2022

Heart Biopsy May Help Diagnose EGPA in ANCA-negative Cases

ANCA Vasculitis News

A biopsy of heart muscle may aid in the diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA) with cardiac involvement in patients negative for antineutrophil cytoplasmic antibodies (ANCAs) and with a ... Read more

May 5, 2022May 5, 2022

Organizations Rally to Help Ukrainian Rare Disease Patients

ANCA Vasculitis News

A Russian military plane crash near Tetiana Zamorska’s home in Kyiv, Ukraine, was a sign that it was time for her and her family to leave. The treacherous, 34-hour pilgrimage that ... Read more

May 4, 2022May 5, 2022

This Year’s Vasculitis Awareness Month – #VAM2022 – Honors ‘Heroes’

ANCA Vasculitis News, COVID-19 News

From honoring healthcare professionals and scientists to spotlighting “patient heroes,” activities are underway for this year’s Vasculitis Awareness Month, dubbed #VAM2022. VAM is observed each May to bring attention to ... Read more

May 2, 2022May 2, 2022

Small RNAs Elevated in Patients’ Urinary Vesicles, Study Shows

ANCA Vasculitis News

Levels of five small RNA molecules were found to be highly elevated in extracellular vesicles — small packets of cellular cargo — found in the urine of people with ANCA-associated ... Read more

April 27, 2022April 27, 2022

Canada OKs Tavneos as Add-on Treatment for MPA and GPA

ANCA Vasculitis News

Health Canada has approved the oral medicine Tavneos (avacopan) as an add-on therapy to treat adults with severe ANCA-associated vasculitis (AAV). The approval specifically covers the use of Tavneos to treat ... Read more