ALS News Today

April 12, 2021April 12, 2021

It’s Official: Each June 2 Will Be ‘Lou Gehrig Day’ for Major League Baseball

ALS News Today

After a protracted campaign to make it happen, Major League Baseball (MLB) agreed to set aside each June 2 to pay tribute to the late Lou Gehrig, the legendary New ... Read more

April 9, 2021April 9, 2021

Invitae Opens Genetic Testing to Adults With ALS Symptoms or Family Risk

ALS News Today

People at risk or suspected of having some of the most common neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), may now access a genetic test at no charge that could ... Read more

April 8, 2021April 8, 2021

Maze Therapeutics Advances Potential Gene Therapy Involving ATXN2

ALS News Today

Maze Therapeutics is advancing the development of a lead gene therapy candidate for amyotrophic lateral sclerosis (ALS), which works by suppressing the activity of a potent genetic modifier called ATXN2. Genetic modifiers ... Read more

April 7, 2021April 7, 2021

Ionis Opening Phase 3 Trial of ION363, Antisense Therapy for FUS-ALS

ALS News Today

Ionis Pharmaceuticals is opening a Phase 3 safety and efficacy trial of ION363 (jacifusen) in amyotrophic lateral sclerosis (ALS) patients with confirmed mutations in the FUS gene, a known cause of juvenile-onset ... Read more

April 6, 2021April 6, 2021

NIH Grant Supports Research Into FUS Mutations, Protein Toxicity

ALS News Today

The National Institutes of Health (NIH) has awarded a $450,000 grant to a university research team to explore mutations in the FUS gene that contribute to amyotrophic lateral sclerosis (ALS), ... Read more

April 5, 2021April 5, 2021

ALS-linked Mutations Surprising Common in Absence of Family History

ALS News Today

A higher than expected proportion of amyotrophic lateral sclerosis (ALS) patients — most without a family history of ALS— had mutations in genes associated with the disease, according to a ... Read more

April 2, 2021April 2, 2021

New Study Seeks to Track ALS Progression With Smartphone App

ALS News Today, COVID-19 News

The Muscular Dystrophy Association (MDA) is urging people with amyotrophic lateral sclerosis (ALS) to take part in a new study that’s seeking to track disease progression through a mobile app. ... Read more

April 1, 2021April 1, 2021

Cost of Rare Diseases in US? Nearly $1 Trillion in 2019, EveryLife Foundation Finds

ALS News Today

As anyone affected by a rare disease knows, treating the illness while trying to go about everyday life is an expensive undertaking.  But exactly how expensive — in terms of ... Read more

April 1, 2021April 1, 2021

ALS Groups Give $1.1M More in Support of T-cell Therapy in Phase 2 Trial

ALS News Today

The ALS Association, Muscular Dystrophy Association (MDA), and ALS Finding a Cure have given an additional $1.1 million to support work on a cell therapy — now in a Phase 2 ... Read more

March 31, 2021March 31, 2021

Biogen Declines Early Access to Tofersen Until Pivotal Trial Ends

ALS News Today

Biogen will not offer early access to tofersen, its experimental therapy for familial amyotrophic lateral sclerosis (ALS) caused by mutations in the SOD1 gene, at least until data from its ... Read more

March 30, 2021March 30, 2021

First Patients Dosed in Phase 2 Trial of RT001

ALS News Today

Retrotope has dosed the first patients in its recently-initiated Phase 2 clinical trial evaluating RT001 for the treatment of amyotrophic lateral sclerosis (ALS). Enrollment is open across four European sites ... Read more

March 29, 2021March 29, 2021

‘End ALS Challenge’ Invites AI Community to Tackle 3 Key Questions

ALS News Today

Roche Canada’s Artificial Intelligence Centre of Excellence (AI CoE), in collaboration with Answer ALS and EverythingALS, opened a challenge that asks the global artificial intelligence (AI) community to model solutions ... Read more

March 26, 2021March 26, 2021

Phase 3 Trial of Stem Cell Therapy NeuroNata-R Likely to Expand to US

ALS News Today

A Phase 3 clinical trial is recruiting adults with amyotrophic lateral sclerosis (ALS) to evaluate the safety and effectiveness of NeuroNata-R (lenzumestrocel), a stem cell therapy approved to treat ALS in ... Read more

March 25, 2021March 25, 2021

Cox Offers New Eye-controlled TV Remote for ALS, Other Patients

ALS News Today

A new feature of Cox’s accessible web remote enables people with amyotrophic lateral sclerosis (ALS) and others with disabilities to control their TVs using their eyes. The free remote also ... Read more

March 24, 2021March 24, 2021

‘Becca’ Fundraiser Set for May 4 to Honor Broadway Star Who Died of ALS

ALS News Today

To honor the memory of Broadway actor and singer Rebecca Luker, who died of complications due to amyotrophic lateral sclerosis (ALS) last year, Target ALS will present a live-streamed concert ... Read more