Posts by: Marisa Wexler

A new research project seeks to better characterize the structural properties of alpha-synuclein, which researchers hope will lead to a better understanding of this protein’s toxic effects in Parkinson’s disease. ... Read more

October 15, 2021October 15, 2021

Epilepsy Therapy Zonisamide Found to Reduce Parkinson’s ‘Off’ Time

Parkinson's News Today

Treatment with zonisamide — an approved epilepsy medication — can reduce “off” time without worsening treatment side effects in people with Parkinson’s disease, a new analysis of Japanese clinical trial ... Read more

October 11, 2021October 11, 2021

GCase Enzyme Activity Not Linked to Parkinson’s Risk, Severity

Parkinson's News Today

The activity of the enzyme glucocerebrosidase, called GCase, is not tied to the risk of developing Parkinson’s, nor linked with the disease’s severity, a new analysis from Israel indicates. “We ... Read more

October 6, 2021October 6, 2021

Oral ANVS401 Improves Patients’ Motor Skills in Phase 2 Trial

Parkinson's News Today

Once-a-day treatment with oral ANVS401 was found to significantly improve motor skills among Parkinson’s disease patients in a Phase 2a clinical trial. Annovis Bio, the company developing ANVS401, is now planning to ... Read more

October 4, 2021October 4, 2021

SBT-272, Supporting Mitochondria, Eases Disease Symptoms in Mice

Parkinson's News Today

Treatment with an investigational medicine called SBT-272 markedly eased signs of Parkinson’s disease in a mouse model, according to its developer Stealth BioTherapeutics. “We are excited about the promise of ... Read more

October 1, 2021October 1, 2021

Blocking 2 Proteins Might Stop Spread of Alpha-synuclein in Brain

Parkinson's News Today

The spread of alpha-synuclein aggregates in the brain is dependent on a protein receptor called TLR2, and also a transcription factor called NF-KB, a study indicates. Blocking these proteins — ... Read more

September 30, 2021September 30, 2021

ParkinSense Startup Advancing New Motor Symptom Monitoring System

Parkinson's News Today

ParkinSense, an upcoming startup out of the University of Toronto, has secured funding to advance a new monitoring system that’s designed to better assess tremors and other motor symptoms in ... Read more

September 29, 2021September 29, 2021

Changes in Oil on Skin’s Surface May Help to Diagnose Parkinson’s

Parkinson's News Today

Changes in the genetic material of the sebum — the “oil” on the skin’s surface — are evident in people with Parkinson’s, and analyzing this skin surface lipid may aid ... Read more

September 28, 2021September 28, 2021

Study Explores Imbalances in Brain That Lead to LID

Parkinson's News Today

An imbalance between the signaling molecules dopamine and sonic hedgehog in the brain may be the cause of the movement disorder caused by dopamine-replacing medicines used to treat Parkinson’s disease. ... Read more

September 23, 2021September 23, 2021

Carnivorous Plants Inspire Researchers to Build Better Brain Implants

Parkinson's News Today

Taking inspiration from carnivorous plants, researchers in Korea have developed new technology that may increase the longevity of surgical devices implanted into the brain. The research may lead to improvements ... Read more

September 21, 2021September 21, 2021

Model That Can Predict Placebo Effect May Help Clinical Researchers

Parkinson's News Today

Using a novel approach, called Placebell, could help researchers in clinical trials to understand the placebo effect in people with Parkinson’s disease, and boost the strength of their findings. Researchers ... Read more

September 13, 2021September 13, 2021

Small Molecules, STARs Treat Cell Models of GBA1-linked Parkinson’s

Parkinson's News Today

Two investigational small molecules known as GT-02287 and GT-02329 lowered toxic protein levels in patient-derived cell models of Parkinson’s disease associated with a mutation in GBA1, their developer, Gain Therapeutics, announced. Gain ... Read more

September 10, 2021September 10, 2021

Variety of Ways to Help Patients With Walking Not Widely Known

Parkinson's News Today

People with gait difficulties due to Parkinson’s disease make adjustments that aid in walking, but many are not aware of the variety of “compensation strategies” available to them, a study based on ... Read more

September 2, 2021September 2, 2021

B-SOiD Algorithm May Make it Easier to Study Behavior

Parkinson's News Today

A novel machine learning algorithm called B-SOiD quickly and efficiently analyzes animal behaviors, and may be useful in assessing movement disorders in people with Parkinson’s disease. Researchers described their findings in ... Read more

September 1, 2021September 1, 2021

Many Patients Harbor Misconceptions About Vaccines

COVID-19 News, Parkinson's News Today

Many people with Parkinson’s disease have misconceptions about routine vaccinations, with more than one of 10 patients thinking they are not recommended for people with Parkinson’s — even though they ... Read more