Same C5a Complement Protein Mechanisms Found in aHUS, COVID-19

Same C5a Complement Protein Mechanisms Found in aHUS, COVID-19

316118

Same C5a Complement Protein Mechanisms Found in aHUS, COVID-19

C5a, a terminal product of the complement system, can, by itself, promote blood vessel dysfunction and the subsequent formation of blood clots seen in people with atypical hemolytic uremic syndrome (aHUS), a study shows. Notably, the same C5a-induced molecular mechanisms were detected among patients with severe COVID-19 and whose infection triggered complement system activation. These findings highlight C5a as a common blood clotting-inducer in diseases characterized by an overly active complement system and suggest that suppressing…

You must be logged in to read/download the full post.