Immune Dysfunction Common in Hypermobile EDS, Study Finds

Immune Dysfunction Common in Hypermobile EDS, Study Finds

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Immune Dysfunction Common in Hypermobile EDS, Study Finds

Immune dysfunction — including abnormal activation of mast cells and antibody deficiency — is common among people with hypermobile Ehlers–Danlos syndrome (hEDS) and those with hypermobile spectrum disorder (HSD), according to a U.S. study. These findings suggest that hEDS and its associated tissue fragility may increase the susceptibility to immune problems, such as the abnormal activation of mast cells, tissue-resident immune cells that are activated by tissue damage and drive allergic reactions. Further studies are…

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