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MECP2 May Regulate Behavioral Effects of Early Life Stresses

The MECP2 gene — mutations in which cause most cases of Rett syndrome — may be important for encoding early childhood traumas into the genetic wiring of the brain, affecting behaviors, a study in mice suggests. Titled “MeCP2 haplodeficiency and early-life stress interaction on anxiety-like behavior in adolescent female mice,” the study was published in the Journal of Neurodevelopmental Disorders. The MECP2 gene provides instructions for making a protein of the same name. The MeCP2 protein is thought…