Iron Buildup May Lead to Death of CF Airway Cells, Study Suggests

Iron Buildup May Lead to Death of CF Airway Cells, Study Suggests

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Iron Buildup May Lead to Death of CF Airway Cells, Study Suggests

Airway cells in cystic fibrosis (CF) were more susceptible to death due to the buildup of iron and their reduced antioxidant ability, a study suggested. These findings support further research into the use of iron-binding chelators and antioxidants as potential CF therapies, the scientists said. The study, “Increased susceptibility of cystic fibrosis airway epithelial cells to ferroptosis,” was published in the journal Biological Research. In CF, a faulty CFTR protein leads to abnormal transport of…

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