IPF Progression Linked to Increased Type VI Collagen Formation in Study

IPF Progression Linked to Increased Type VI Collagen Formation in Study

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IPF Progression Linked to Increased Type VI Collagen Formation in Study

Idiopathic pulmonary fibrosis (IPF) patients with increased formation of type VI collagen — a major extracellular matrix (ECM) molecule involved in wound healing and scarring — are at higher risk of having progressive disease, a real-world study shows. Also, type VI collagen breakdown tended to increase in patients with progressive disease and normalize in those receiving anti-scarring therapies. These findings add to previous studies showing an association between increased formation and degradation of other types of…

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