Nerve Damage Seen in Skin Can Predict Parkinson’s Progression

Nerve Damage Seen in Skin Can Predict Parkinson’s Progression

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Nerve Damage Seen in Skin Can Predict Parkinson’s Progression

In Parkinson’s patients, greater nerve damage in the skin around the ankle is significantly associated with subsequent progression of motor symptoms, while the presence of such damage in neck skin is linked to progressive cognitive decline, a study shows. Notably, this nerve damage progression was not related to increased skin levels of damaging forms of alpha-synuclein, the protein that aggregates into toxic clumps in Parkinson’s. Still, a combination of alpha-synuclein forms with nerve fiber damage…

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