Blood Levels of Proteins Identify Active AAV in Long-term Study

Blood Levels of Proteins Identify Active AAV in Long-term Study

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Blood Levels of Proteins Identify Active AAV in Long-term Study

Blood levels of several proteins — CXCL13, interleukins IL-6, IL-8, IL-15, IL-18 binding protein (IL-18BP), matrix metalloproteinase-3 (MMP-3), and erythrocyte sedimentation rate (ESR) — were validated as effective at identifying active ANCA-associated vasculitis (AAV) in a long-term study. The study, “Serum Biomarkers of Disease Activity in Longitudinal Assessment of Patients with ANCA-Associated Vasculitis,” was published in the journal ACR Open Rheumatology. AAV is a group of autoimmune diseases characterized by inflammation and damage to small…

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