Blocking Protein of Glucose Uptake, SGLT1, May Help in Treating CF

Blocking Protein of Glucose Uptake, SGLT1, May Help in Treating CF

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Blocking Protein of Glucose Uptake, SGLT1, May Help in Treating CF

Blocking the protein SGLT1, which regulates glucose uptake in cells, may be a useful in treating cystic fibrosis (CF), according to research done in a cell model of the disease. SGLT1 inhibitors are likely less effective that currently approved modulators for patients with eligible mutations, its scientists noted, but they could have “synergistic effects” when used in combination. Findings were in the study, “The sodium/glucose cotransporters as potential therapeutic targets for cystic fibrosis lung diseases revealed…

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