Researchers Shed Light on Link Between Nuclear Protein and MS

Researchers Shed Light on Link Between Nuclear Protein and MS

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Researchers Shed Light on Link Between Nuclear Protein and MS

A nuclear protein called heterogeneous nuclear ribonucleoprotein A1 or hnRNP A1 — abnormally found outside the nucleus in people with neurodegenerative diseases such as multiple sclerosis (MS) — is essential for nerve cell function and survival. Those are the findings of a new study, by Canadian researchers, of nerve cells grown in the lab. Combined with previous data showing that hnRNP A1 mislocalization is associated with the formation of toxic, persistent stress granules, these findings…

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