Tau Protein in Alzheimer’s Linked to ALS Mitochondrial Dysfunction

Tau Protein in Alzheimer’s Linked to ALS Mitochondrial Dysfunction

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Tau Protein in Alzheimer’s Linked to ALS Mitochondrial Dysfunction

An abnormal version of tau, a protein associated with Alzheimer’s disease, may contribute to the progression of amyotrophic lateral sclerosis (ALS) by damaging mitochondria in neurons, according to a new study. The findings suggest that decreasing tau levels might be a new therapeutic strategy to lessen mitochondrial dysfunction in ALS. “We demonstrated for the first time that targeting tau with a new class of small molecules that selectively degrade it can reverse the ALS-induced changes…

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