Lung Airway Chip Accurately Models Cystic Fibrosis

Lung Airway Chip Accurately Models Cystic Fibrosis

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Lung Airway Chip Accurately Models Cystic Fibrosis

For the first time, many features of cystic fibrosis (CF) were modeled accurately in a human Lung Airway Chip lined with cells from CF patients, which included enhanced mucus secretion, inflammation, and microbial infections, a study has shown. This “organ-on-a-chip model” of the disease may support the rapid development of much-needed therapies, with the potential of personalized medications for CF patients. “Now that we are able to accurately model CF [disease], including microbiome and inflammatory…

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