Elexacaftor Also Works as CFTR Potentiator, Study Says

Elexacaftor Also Works as CFTR Potentiator, Study Says

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Elexacaftor Also Works as CFTR Potentiator, Study Says

Elexacaftor (VX-445), a next-generation CFTR corrector that is part of the triple-combination therapy Trikafta, is also a potentiator, a study reports. Results further showed that in combination with ivacaftor, sold as Kalydeco and also a potentiator, elexacaftor boosts ion flow across CFTR, the channel protein that is defective in people with cystic fibrosis (CF) These findings support the therapeutic potential of this new combo, scientists said. The study, “Elexacaftor is a CFTR potentiator and acts synergistically with…

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