Study Sheds Light on How Tecfidera Kills Immune Cells

Study Sheds Light on How Tecfidera Kills Immune Cells

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Study Sheds Light on How Tecfidera Kills Immune Cells

The multiple sclerosis (MS) treatment Tecfidera (dimethyl fumarate) triggers immune cell death by interacting with a protein called Keap-1, a new study reveals. The study, “Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera,” was published in Nature Communications. Tecfidera is widely approved to treat relapsing types of MS. The name-brand medicine is marketed by Biogen; generic forms also are available. Tecfidera is thought to work broadly by reducing the inflammatory immune attack…

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