Blood Levels of Endostatin Seen to Aid Models of Likely PAH Outcomes

Blood Levels of Endostatin Seen to Aid Models of Likely PAH Outcomes

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Blood Levels of Endostatin Seen to Aid Models of Likely PAH Outcomes

Circulating endostatin, a protein that inhibits new blood vessel formation, appears to correlate well with mortality and disease severity in people with pulmonary arterial hypertension (PAH) in a large, observational study. Blood levels of endostatin show a “clear potential … as a robust prognostic biomarker in PAH” and could help assessments by being added to existing PAH risk predictive models, its researchers wrote. Significant associations between these levels and mortality were particularly evident in idiopathic…

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