MeCP2 Protein Defects Led to RNA Errors in Brains of Rett Mice

MeCP2 Protein Defects Led to RNA Errors in Brains of Rett Mice

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MeCP2 Protein Defects Led to RNA Errors in Brains of Rett Mice

Impaired function of the MeCP2 protein — the most common cause of Rett syndrome — causes defects in a process called RNA splicing, affecting protein production from genes important for nerve cell communication. The study with that finding, “Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models,” was published in the journal Nature Communications. While the MeCP2 protein, derived from the MECP2 gene, is found in several tissues, it is highly…

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