PWS Caregivers Trade Risk of Treatment Side Effects for Less Hyperphagia

PWS Caregivers Trade Risk of Treatment Side Effects for Less Hyperphagia

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PWS Caregivers Trade Risk of Treatment Side Effects for Less Hyperphagia

In return for a reduction in the abnormal hunger and excessive eating, called hyperphagia, that characterizes Prader-Willi syndrome (PWS), caregivers of patients with the rare genetic disease — even many who did not identify as risk-takers — are willing to accept medications with a potential for side effects, including skin-picking and liver damage, a study reports. Given that “concerns persist regarding the meaningfulness of hyperphagia as a clinical endpoint” or goal in therapy development, these…

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