Compound Works to Ease Brain Inflammation Driven by Glial Cells

Compound Works to Ease Brain Inflammation Driven by Glial Cells

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Compound Works to Ease Brain Inflammation Driven by Glial Cells

A molecule that blocks the regulatory RNA protein HuR, called SRI-42127, strongly reduces brain inflammation driven by activated glial cells, key players in neurodegenerative diseases like amyotrophic lateral sclerosis, a preclinical study reported. This inhibitor may be of promise in treating ALS and other diseases driven by inflammation in the brain. “Our findings underscore HuR’s critical role in promoting glial activation and the potential for SRI-42127 and other HuR inhibitors to treat neurological diseases driven by this activation,”…

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