Study of Gene Activity in Endothelial Cells Aims to Better Treat PAH

Study of Gene Activity in Endothelial Cells Aims to Better Treat PAH

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Study of Gene Activity in Endothelial Cells Aims to Better Treat PAH

Potential targets to treat pulmonary arterial hypertension (PAH) were identified by analyzing the gene activity of individual lung endothelial cells isolated from a mouse model of the disease. Study results were validated by cross-referencing them with rat and human gene activity datasets. “The identification of distinct molecular mechanisms and potential therapeutic targets is crucial for the future development of pharmacological interventions targeting endothelial dysfunction,” the researchers wrote. The study, “Single-cell RNA-seq profiling of mouse endothelial…

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