Genetic Analysis Spots Cancer Therapies With Potential to Treat PH

Genetic Analysis Spots Cancer Therapies With Potential to Treat PH

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Genetic Analysis Spots Cancer Therapies With Potential to Treat PH

By analyzing how medications affect the genetic activity of cells, researchers developed a computational pipeline that may be useful in repurposing cancer treatments for use in other diseases. Leveraging this pipeline, the team identified two compounds, I-BET762 and BRD2889, that might be refined — more quickly and at lower cost than new compounds — to treat pulmonary hypertension (PH). Results were described in the study, “Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension,”…

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