Epilepsy Therapy Zonisamide Found to Reduce Parkinson’s ‘Off’ Time

Epilepsy Therapy Zonisamide Found to Reduce Parkinson’s ‘Off’ Time

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Epilepsy Therapy Zonisamide Found to Reduce Parkinson’s ‘Off’ Time

Treatment with zonisamide — an approved epilepsy medication — can reduce “off” time without worsening treatment side effects in people with Parkinson’s disease, a new analysis of Japanese clinical trial data shows. Notably, the use of zonisamide did not increase dyskinesia, the uncontrolled, involuntary movements common among Parkinson’s patients undergoing treatment for the neurodegenerative disorder. “Zonisamide improves wearing off [off time] without exacerbating dyskinesia in Japanese patients with [Parkinson’s disease],” the researchers wrote. The results…

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