New PET Tracer May Better Capture Brain Inflammation in ALS

New PET Tracer May Better Capture Brain Inflammation in ALS

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New PET Tracer May Better Capture Brain Inflammation in ALS

An imaging agent developed by Ashvattha Therapeutics can accurately detect brain inflammation caused by microglia, immune cells that play a key role in neurological diseases such as amyotrophic lateral sclerosis (ALS), a mouse study reported. The company is planning to initiate a Phase 1/2 clinical trial in ALS patients next year, using its PET tracer to help determine the efficacy of OP-101, a candidate therapy to prevent neuroinflammation by targeting microglia in the brain. Imaging findings were…

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