JC Virus Mutations May Predict Rare Brain Infection Linked to Tysabri

JC Virus Mutations May Predict Rare Brain Infection Linked to Tysabri

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JC Virus Mutations May Predict Rare Brain Infection Linked to Tysabri

Mutations in the John Cunningham virus may serve as an early predictor for a rare brain infection in multiple sclerosis patients receiving Tysabri (natalizumab), a study suggests. However, more research is required to investigate the specific mutations in the viral VP1 gene, and validate the risk of the condition, known as progressive multifocal leukoencephalopathy (PML), in a larger group of MS patients. The study, “Mutations in the John Cunningham virus VP1 gene could predispose to…

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