Repeat Lung Injury Depletes Stem Cell Pool There, May Promote COPD

Repeat Lung Injury Depletes Stem Cell Pool There, May Promote COPD

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Repeat Lung Injury Depletes Stem Cell Pool There, May Promote COPD

Repeated lung injury increases the biological age of lung stem cells and progressively diminishes their regenerative abilities, according to a study in mice and lab-grown human cells. These findings suggest that such repeat damage contributes to the abnormal repair and tissue remodeling that characterizes chronic obstructive pulmonary disease (COPD) and other chronic lung diseases, the researchers noted. “This premature aging of the tracheobronchial stem cells (TSCs) in turn may contribute to chronic lung disease,” Susan D.…

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