Cancer Researchers’ Discovery May Benefit MS Studies

Cancer Researchers’ Discovery May Benefit MS Studies

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Cancer Researchers’ Discovery May Benefit MS Studies

In an unexpected discovery, scientists working to understand the biological underpinnings of brain tumors found that increasing the activity of a protein receptor called PDGFRA reduces the production of myelin — the fatty coating that is lost in multiple sclerosis (MS) — in the nervous system. “We saw that too much PDGFRA interfered with differentiation of progenitor cells that give rise to cells that make myelin,” one of the researchers, Oren Becher, MD, from Ann…

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