Hormones, Signaling Proteins in SSc Altered With BMI, Analysis Finds

Hormones, Signaling Proteins in SSc Altered With BMI, Analysis Finds

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Hormones, Signaling Proteins in SSc Altered With BMI, Analysis Finds

Altered levels of immune signaling proteins (cytokines) and fat-based hormones in systemic sclerosis (SSc) are associated with changes in body mass, a blood analysis determined. Researchers say their findings suggest that “an abnormal twist … takes place in SSc” between the immune signaling proteins, these hormones, and body mass index or BMI, a measure of body fat based on height and weight. “Further investigation is warranted to establish whether these findings may represent the pathogenetic [disease-related] background of…

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