Variant in Androgen Receptor Might Be Useful in Treating SBMA

Variant in Androgen Receptor Might Be Useful in Treating SBMA

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Variant in Androgen Receptor Might Be Useful in Treating SBMA

A naturally occurring form of the androgen receptor protein — which scientists have named AR45 because of its size — may be useful for treating spinal and bulbar muscular atrophy (SBMA), a rare form of adult-onset spinal muscular atrophy, a new study suggests. In the lab, a treatment using AR45 was found to delay disease onset in a mouse model of SBMA, also called Kennedy’s disease, and to extend the animals’ survival. “A study published in…

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