Study Shows Value of Biofilm Component in P. aeruginosa Resistance

Study Shows Value of Biofilm Component in P. aeruginosa Resistance

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Study Shows Value of Biofilm Component in P. aeruginosa Resistance

Differences in Psl, a complex sugar molecule produced by Pseudomonas aeruginosa, contribute to the bacterium’s resistance against the antibiotic tobramycin in children with cystic fibrosis (CF), a study shows. While tobramycin-resistant P. aeruginosa produced similar levels of Psl to those that were effectively eradicated with the antibiotic, its Psl molecules exhibited different binding profiles that affected the bacterium’s ability to aggregate and resist tobramycin. However, since these results were based on bacteria collected from children with CF…

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