CAR T-cell Therapy Descartes-08 Eased MG Symptoms

CAR T-cell Therapy Descartes-08 Eased MG Symptoms

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CAR T-cell Therapy Descartes-08 Eased MG Symptoms

Treatment with Descartes-08, an investigational CAR T-cell therapy, markedly eased symptoms of myasthenia gravis (MG) in three patients participating in a Phase 1/2 clinical trial assessing the therapy’s safety and preliminary efficacy. “This is the first clinical trial of CAR T-cells for an autoimmune disease. Naturally, the first patients enrolled are some of our most severely affected and difficult-to-treat patients, who have been followed for many years,” trial investigator Tahseen Mozaffar, MD, of the University…

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