MG Genetic Risk Factor Directly Tied to Neuromuscular Junction Identified

MG Genetic Risk Factor Directly Tied to Neuromuscular Junction Identified

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MG Genetic Risk Factor Directly Tied to Neuromuscular Junction Identified

For the first time, a genetic risk factor for myasthenia gravis (MG) has been identified that involves a gene — AGRN — coding for a protein directly involved in the activity of neuromuscular junctions (NMJs), which are impaired in MG, researchers report. The study, involving the genetic analysis of more than 1,000 MG patients and 3,500 healthy individuals of European ancestry, also confirmed the protective or damaging effects of genetic variants previously associated with MG. Data also…

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