Vitamin D Eases Lung Fibrosis by Blocking RAS Pathway, Study Finds

Vitamin D Eases Lung Fibrosis by Blocking RAS Pathway, Study Finds

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Vitamin D Eases Lung Fibrosis by Blocking RAS Pathway, Study Finds

Treatment with vitamin D’s active form lessened lung scarring, and significantly reduced the levels of fibrotic markers in a mouse model of idiopathic pulmonary fibrosis (IPF), a study reported. Notably, these benefits were associated with vitamin D’s suppression of the renin-angiotensin system (RAS), whose chronic activation promotes the production of pro-fibrotic molecules and the development of lung fibrosis (scarring). Losartan, an approved blood pressure medication that works by suppressing RAS, also eased fibrosis in the animals’…

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