Way of Protecting Key Neurons in LRRK2-linked Parkinson’s Seen

Way of Protecting Key Neurons in LRRK2-linked Parkinson’s Seen

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Way of Protecting Key Neurons in LRRK2-linked Parkinson’s Seen

In mice with a harmful mutation in the leucine-rich repeat protein kinase 2 (LRRK2) gene, one of the most common genetic causes of Parkinson’s disease, treatment with a small molecule compound restored the recycling of damaged mitochondria — the cells’ powerhouses — from dopamine-producing nerve cells. A failure to remove damaged mitochondria — a normal and essential quality control process for cells — is thought to kill these nerve cells in the brains of Parkinson’s…

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