Rituximab Found to Be Safe, Effective for 2 AAV Types in Children

Rituximab Found to Be Safe, Effective for 2 AAV Types in Children

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Rituximab Found to Be Safe, Effective for 2 AAV Types in Children

Rituximab is safe and effective for inducing remission in two types of ANCA-associated vasculitis in children and adolescents: granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA), according to data from a Phase 2a trial. After one and a half years on the trial, all patients achieved remission, and safety data was consistent with data from adults with the disease. Findings from this trial supported the U.S. and European approvals of rituximab, in combination with glucocorticoids,…

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